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Interferon gamma Antikörper

IFNG Reaktivität: Human WB, ELISA Monoclonal unconjugated
Produktnummer ABIN966336
  • Target Alle Interferon gamma (IFNG) Antikörper anzeigen
    Interferon gamma (IFNG)
    Reaktivität
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    Human
    Wirt
    Bitte anfragen
    Klonalität
    • 287
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    • 1
    Monoklonal
    Konjugat
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    Dieser Interferon gamma Antikörper ist unkonjugiert
    Applikation
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    Western Blotting (WB), ELISA
    Spezifität
    Ni-NTA purified recombinant human IFN-gamma expressed in E. Coli strain BL21 (DE3)
    Aufreinigung
    Antibodies are purified by protein A affinity chromatography
    Isotyp
    IgG1
    Top Product
    Discover our top product IFNG Primärantikörper
  • Applikationshinweise
    Dilution: Western Blot: 1:500-1,000
    ELISA: Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    -20 °C
  • Tsubota, Fukagawa, Fujihara, Shimmura, Saito, Saito, Takeuchi: "Regulation of human leukocyte antigen expression in human conjunctival epithelium." in: Investigative ophthalmology & visual science, Vol. 40, Issue 1, pp. 28-34, (1999) (PubMed).

  • Target
    Interferon gamma (IFNG)
    Andere Bezeichnung
    IFN-Y (IFNG Produkte)
    Synonyme
    IFG antikoerper, IFI antikoerper, IFN-g antikoerper, Ifg antikoerper, IFNG2 antikoerper, IFN-gamma antikoerper, IFN-G antikoerper, IFNG antikoerper, IFNgamma antikoerper, TCRalpha antikoerper, INF-G antikoerper, ifng antikoerper, interferon gamma antikoerper, interferon, gamma 1-2 antikoerper, IFNG antikoerper, Ifng antikoerper, ifng1-2 antikoerper
    Hintergrund
    Interferon-gamma (IFN-gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-gamma strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.
    Gen-ID
    3458
    Pathways
    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie
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