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HTR2A Antikörper (C-Term)
HTR2A
Reaktivität: Human, Maus, Ratte
WB, IHC (p)
Polyclonal
unconjugated
Produktdetails anti-HTR2A Antikörper
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Target
Alle HTR2A Antikörper anzeigen
HTR2A
(5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
Bindungsspezifität
Alle Epitope für HTR2A Antikörper
AA 418-432, C-Term
Reaktivität
Alle Reaktivitäten für HTR2A Antikörper
Human, Maus, Ratte
Wirt
Bitte anfragen
Klonalität
Alle Klonalitäten für HTR2A Antikörper
Polyklonal
Konjugat
Alle Konjugate für HTR2A Antikörper
Dieser HTR2A Antikörper ist unkonjugiert
Applikation
Alle Applikationen für HTR2A Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminal of human HTR2A (418-432 aa), different from the mouse sequence by one amino acid.
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Discover our top product HTR2A Primärantikörper
Alternativen
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Anwendungsinformationen
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Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Konservierungsmittel
Thimerosal (Merthiolate), Sodium azide
Lagerung
-20 °C
Referenzen für anti-HTR2A Antikörper (ABIN966325)
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Elphick, Querbes, Jordan, Gee, Eash, Manley, Dugan, Stanifer, Bhatnagar, Kroeze, Roth, Atwood : "The human polyomavirus, JCV, uses serotonin receptors to infect cells. " in: Science (New York, N.Y.) , Vol. 306 , Issue 5700 , pp. 1380-3 , (2004 ) (PubMed ).
Cook, Fletcher, Wainwright, Marks, Yan, Leventhal : "Primary structure of the human platelet serotonin 5-HT2A receptor: identify with frontal cortex serotonin 5-HT2A receptor. " in: Journal of neurochemistry , Vol. 63 , Issue 2 , pp. 465-9 , (1994 ) (PubMed ).
Details zu HTR2A
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Target
HTR2A
(5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))
Andere Bezeichnung
HTR2A (HTR2A Produkte )
Synonyme
5-HT2A antikoerper, HTR2 antikoerper, 5-HT-2 antikoerper, 5-HT-2A antikoerper, 5-HTR2A antikoerper, LOC100009461 antikoerper, E030013E04 antikoerper, Htr-2 antikoerper, Htr2 antikoerper, 5Ht-2 antikoerper, 5HT2A antikoerper, 5HTR2A antikoerper, HTR2A antikoerper, Htr2a antikoerper, 5HT2 antikoerper, 5-hydroxytryptamine receptor 2A antikoerper, 5-hydroxytryptamine (serotonin) receptor 2A antikoerper, HTR2A antikoerper, Htr2a antikoerper
Hintergrund
The mammalian HTR2A 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). This is the main excitatory receptor subtype among the GPCRs for serotonin (5-HT), although 5-HT2A may also have an inhibitory effect on certain areas such as the visual cortex and the orbit frontal cortex. This receptor was given importance first as the target of psychedelic drugs like LSD. Later it came back to prominence because it was also found to be mediating, at least partly, the action of many antipsychotic drugs, especially the atypical ones.5-HT2A also happens to be a necessary receptor for the spread of the human polyoma virus called JC virus. Sparkes et al. (1991) concluded that the gene is located on 13q14-q21 in man and on chromosome 14 in the mouse.
Pathways
JAK-STAT Signalweg , Inositol Metabolic Process , Regulation of Carbohydrate Metabolic Process
Zuletzt angesehen
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