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Glucagon Antikörper

GCG Reaktivität: Human ELISA, WB Wirt: Maus Monoclonal 2F9 unconjugated
Produktnummer ABIN966191
  • Target Alle Glucagon (GCG) Antikörper anzeigen
    Glucagon (GCG)
    Reaktivität
    • 119
    • 48
    • 43
    • 14
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 77
    • 30
    • 14
    • 4
    • 1
    Maus
    Klonalität
    • 84
    • 41
    Monoklonal
    Konjugat
    • 77
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Glucagon Antikörper ist unkonjugiert
    Applikation
    • 53
    • 50
    • 29
    • 16
    • 14
    • 13
    • 13
    • 12
    • 12
    • 11
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB)
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human GCG expressed in E. Coli.
    Klon
    2F9
    Isotyp
    IgG1
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  • Applikationshinweise
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Geliebter, Hashim, Gluck: "Appetite-related gut peptides, ghrelin, PYY, and GLP-1 in obese women with and without binge eating disorder (BED)." in: Physiology & behavior, Vol. 94, Issue 5, pp. 696-9, (2008) (PubMed).

    Arnés, González, Tornero-Esteban, Sancho, Acitores, Valverde, Delgado, Villanueva-Peñacarrillo: "Characteristics of GLP-1 and exendins action upon glucose transport and metabolism in type 2 diabetic rat skeletal muscle." in: International journal of molecular medicine, Vol. 22, Issue 1, pp. 127-32, (2008) (PubMed).

  • Target
    Glucagon (GCG)
    Andere Bezeichnung
    GCG (GCG Produkte)
    Synonyme
    GLP1 antikoerper, GLP2 antikoerper, GRPP antikoerper, GLP-1 antikoerper, Glu antikoerper, PPG antikoerper, GCG antikoerper, gcg-A antikoerper, gcg1 antikoerper, glucagon antikoerper, glucagon L homeolog antikoerper, GCG antikoerper, Gcg antikoerper, gcg.L antikoerper
    Hintergrund
    The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
    Tissue specificity: Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain.
    Synonyms: GLP1, GLP2, GRPP, GCG
    Molekulargewicht
    21kDa
    Gen-ID
    2641
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
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