FOXA2 Antikörper

Produktnummer ABIN966160

Produktdetails anti-FOXA2 Antikörper

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOXA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of FOXA2 expressed in E. Coli.

Klon: 7H4B7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-FOXA2 Antikörper (ABIN966160)

Ishii, Yoshida, Akechi, Sakabe, Nishio, Ikeda, Terabayashi, Matsumi, Gonda, Okamoto, Takubo, Tajima, Tsuchiya, Hoshikawa, Kurimasa, Umezawa, Shiota: "Hepatic differentiation of human bone marrow-derived mesenchymal stem cells by tetracycline-regulated hepatocyte nuclear factor 3beta." in: Hepatology (Baltimore, Md.), Vol. 48, Issue 2, pp. 597-606, (2008) (PubMed).

Halmos, Bassères, Monti, DAló, Dayaram, Ferenczi, Wouters, Huettner, Golub, Tenen: "A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer." in: Cancer research, Vol. 64, Issue 12, pp. 4137-47, (2004) (PubMed).

Details zu FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Andere Bezeichnung: FOXA2 (FOXA2 Produkte)

Synonyme: hnf3b antikoerper, tcf3b antikoerper, hnf3beta antikoerper, hnf3-beta antikoerper, FOXA2 antikoerper, HNF3B antikoerper, TCF3B antikoerper, HNF-3B antikoerper, ax antikoerper, axl antikoerper, fkd1 antikoerper, ik:tdsubc_2g8 antikoerper, tdsubc_2g8 antikoerper, wu:fe05g04 antikoerper, xx:tdsubc_2g8 antikoerper, FoxA2-A antikoerper, FoxA2a antikoerper, xFD-3 antikoerper, xbeta-1 antikoerper, HNF-3b antikoerper, HNF3-beta antikoerper, HNF3beta antikoerper, Hnf-3b antikoerper, Hnf3b antikoerper, Tcf-3b antikoerper, Tcf3b antikoerper, HNF-3BETA antikoerper, forkhead box A2 antikoerper, forkhead box A2 L homeolog antikoerper, foxa2 antikoerper, FOXA2 antikoerper, foxa2.L antikoerper, Foxa2 antikoerper

Hintergrund: FOXA2 (forkhead box A2), also known as HNF3B (hepatocyte nuclear factor 3, beta). It is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for FOXA2.
Synonyms: HNF3B, TCF3B, MGC19807

Molekulargewicht: 48kDa

Gen-ID: 3170

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process