FGF1 Antikörper (C-Term)

Produktnummer ABIN966136

Produktdetails anti-FGF1 Antikörper

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Bitte anfragen

Klonalität: Polyklonal

Konjugat: Dieser FGF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human FGF1, identical to the related rat and mouse sequence.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Lagerung: -20 °C

Referenzen für anti-FGF1 Antikörper (ABIN966136)

Le Beau, Espinosa, Neuman, Stock, Roulston, Larson, Keinanen, Westbrook: "Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 12, pp. 5484-8, (1993) (PubMed).

Mergia, Eddy, Abraham, Fiddes, Shows: "The genes for basic and acidic fibroblast growth factors are on different human chromosomes." in: Biochemical and biophysical research communications, Vol. 138, Issue 2, pp. 644-51, (1986) (PubMed).

Burgess, Mehlman, Marshak, Fraser, Maciag: "Structural evidence that endothelial cell growth factor beta is the precursor of both endothelial cell growth factor alpha and acidic fibroblast growth factor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 19, pp. 7216-20, (1986) (PubMed).

Details zu FGF1

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Andere Bezeichnung: FGF1 (FGF1 Produkte)

Synonyme: AFGF antikoerper, ECGF antikoerper, ECGF-beta antikoerper, ECGFA antikoerper, ECGFB antikoerper, FGF-1 antikoerper, FGF-alpha antikoerper, FGFA antikoerper, GLIO703 antikoerper, HBGF-1 antikoerper, HBGF1 antikoerper, Fgf1 antikoerper, FGF1 antikoerper, aFGF antikoerper, ecgf antikoerper, fgfa antikoerper, ecgfa antikoerper, ecgfb antikoerper, fgf-1 antikoerper, hbgf1 antikoerper, glio703 antikoerper, ecgf-beta antikoerper, fgf-alpha antikoerper, Dffrx antikoerper, Fam antikoerper, Fgf-1 antikoerper, Fgfa antikoerper, zgc:136885 antikoerper, LOC100221393 antikoerper, fgf1 antikoerper, zgc:73249 antikoerper, fibroblast growth factor 1 antikoerper, fibroblast growth factor 1 L homeolog antikoerper, fibroblast growth factor 1b antikoerper, fibroblast growth factor 1a antikoerper, FGF1 antikoerper, fgf1.L antikoerper, fgf1 antikoerper, Fgf1 antikoerper, fgf1b antikoerper, LOC100221393 antikoerper, fgf1a antikoerper

Hintergrund: Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q311. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Additionally, Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. Alpha-ECGF is also derived from ECGFB in the same manner.2, 3

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung