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EPH Receptor B4 Antikörper

EPHB4 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 5B8F7 unconjugated
Produktnummer ABIN966075
  • Target Alle EPH Receptor B4 (EPHB4) Antikörper anzeigen
    EPH Receptor B4 (EPHB4)
    Reaktivität
    • 44
    • 34
    • 2
    Human
    Wirt
    • 44
    • 13
    • 4
    • 1
    Maus
    Klonalität
    • 45
    • 17
    Monoklonal
    Konjugat
    • 32
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser EPH Receptor B4 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 35
    • 10
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of EphB4 expressed in E. Coli.
    Klon
    5B8F7
    Isotyp
    IgG2a
    Top Product
    Discover our top product EPHB4 Primärantikörper
  • Applikationshinweise
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Chrencik, Brooun, Recht, Kraus, Koolpe, Kolatkar, Bruce, Martiny-Baron, Widmer, Pasquale, Kuhn: "Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity." in: Structure (London, England : 1993), Vol. 14, Issue 2, pp. 321-30, (2006) (PubMed).

    Wu, Suo, Risberg, Karlsson, Villman, Nesland: "Expression of Ephb2 and Ephb4 in breast carcinoma." in: Pathology oncology research : POR, Vol. 10, Issue 1, pp. 26-33, (2004) (PubMed).

  • Target
    EPH Receptor B4 (EPHB4)
    Andere Bezeichnung
    EphB4 (EPHB4 Produkte)
    Synonyme
    HTK antikoerper, MYK1 antikoerper, TYRO11 antikoerper, htk antikoerper, myk1 antikoerper, ephB4a antikoerper, tyro11 antikoerper, ephb4b antikoerper, MGC130997 antikoerper, AI042935 antikoerper, Htk antikoerper, MDK2 antikoerper, Myk1 antikoerper, Tyro11 antikoerper, cb646 antikoerper, ephB4 antikoerper, rtk5 antikoerper, EphB-rtk8 antikoerper, cb417 antikoerper, rtk8 antikoerper, EPH receptor B4 antikoerper, EPH receptor B4 L homeolog antikoerper, EPH receptor B4 S homeolog antikoerper, Eph receptor B4 antikoerper, eph receptor B4a antikoerper, eph receptor B4b antikoerper, EPHB4 antikoerper, ephb4.L antikoerper, ephb4.S antikoerper, ephb4 antikoerper, Ephb4 antikoerper, ephb4a antikoerper, ephb4b antikoerper
    Hintergrund
    EPH receptor B4 (EphB4), with 987-amino acid protein (about 108kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph receptor tyrosine kinases and their ligands, the ephrins, regulate numerous biological processes in developing and adult tissues and have been implicated in cancer progression and in pathological forms of angiogenesis. EphB4 acts as a negative regulator of blood vessel branching and vascular network formation, switching the vascularization program from sprouting angiogenesis to circumferential vessel growth. EphB4 and its ligand ephrinB2 express in several kinds of tumor cells and correlate with tumorigenesis. EphB4 is thus a potential candidate as a predictor of disease outcome in several kinds of tumor and as target for novel therapy.
    Synonyms: HTK, MYK1, TYRO11
    Gen-ID
    2050
    Pathways
    RTK Signalweg
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