EPH Receptor A2 Antikörper

Produktnummer ABIN966072

Produktdetails anti-EPH Receptor A2 Antikörper

Target: EPH Receptor A2 (EPHA2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of EphA2 expressed in E. Coli.

Klon: 1B3C7

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-EPH Receptor A2 Antikörper (ABIN966072)

Landen, Kinch, Sood: "EphA2 as a target for ovarian cancer therapy." in: Expert opinion on therapeutic targets, Vol. 9, Issue 6, pp. 1179-87, (2005) (PubMed).

Details zu EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Andere Bezeichnung: EphA2 (EPHA2 Produkte)

Synonyme: ARCC2 antikoerper, CTPA antikoerper, CTPP1 antikoerper, CTRCT6 antikoerper, ECK antikoerper, epha2 antikoerper, MGC89505 antikoerper, AW545284 antikoerper, Eck antikoerper, Myk2 antikoerper, Sek-2 antikoerper, Sek2 antikoerper, id:ibd5152 antikoerper, rtk6 antikoerper, G42 antikoerper, XE10 antikoerper, epha2-A antikoerper, EPH receptor A2 antikoerper, Eph receptor A2 antikoerper, epoxide hydrolase antikoerper, eph receptor A2 a antikoerper, EPH receptor A2 L homeolog antikoerper, EPHA2 antikoerper, Epha2 antikoerper, epha2 antikoerper, ephA2 antikoerper, epha2a antikoerper, epha2.L antikoerper

Hintergrund: EPH receptor A2 (EphA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.
Synonyms: ECK, EPHA2

Gen-ID: 1969

Pathways: RTK Signalweg