Elf4 Antikörper (C-Term)

Produktnummer ABIN966054

Produktdetails anti-Elf4 Antikörper

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Elf4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ELF4 (ETS-related transcription factor Elf-4)

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu Elf4

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Andere Bezeichnung: ELF4 (Elf4 Produkte)

Synonyme: ELF4 antikoerper, RGD1560743 antikoerper, ELFR antikoerper, MEF antikoerper, AV314029 antikoerper, BC042423 antikoerper, ENSMUSG00000053512 antikoerper, Gm9907 antikoerper, Mef antikoerper, E74 like ETS transcription factor 4 antikoerper, E74-like factor 4 (ets domain transcription factor) antikoerper, ELF4 antikoerper, Elf4 antikoerper

Hintergrund: ELF4 (ETS-related transcription factor Elf-4) is a transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter. ELF4 also transactivates the PRF1 promoter in natural killer (NK) cells. The protein plays a role in the development and function of NK and NK T-cells and in innate immunity. ELF4 interacts via an N-terminal region with the RUNX1 Runt domain and interacts via its C-terminus with PML, this interaction enhances ELF4 transactivation of the bovine lysozyme gene.

Pathways: Positive Regulation of Endopeptidase Activity