DTNBP1 Antikörper (N-Term)

Produktnummer ABIN966013

Produktdetails anti-DTNBP1 Antikörper

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DTNBP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DTNBP1(Dystrobrevin binding protein 1)

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu DTNBP1

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Andere Bezeichnung: DTNBP1(Dystrobrevin binding protein 1) (DTNBP1 Produkte)

Synonyme: 5430437B18Rik antikoerper, AW048963 antikoerper, Bloc1s8 antikoerper, dysbindin antikoerper, sdy antikoerper, BLOC1S8 antikoerper, DBND antikoerper, HPS7 antikoerper, My031 antikoerper, SDY antikoerper, dtnbp1 antikoerper, zgc:56462 antikoerper, MGC83903 antikoerper, dbnd antikoerper, hps7 antikoerper, my031 antikoerper, MGC85477 antikoerper, DTNBP1 antikoerper, CG6856 antikoerper, Ddysb antikoerper, Dmel\\CG6856 antikoerper, si:ch211-285p6.1 antikoerper, dystrobrevin binding protein 1 antikoerper, Dysbindin antikoerper, dystrobrevin binding protein 1a antikoerper, dystrobrevin binding protein 1 L homeolog antikoerper, dystrobrevin binding protein 1 S homeolog antikoerper, dystrobrevin binding protein 1b antikoerper, Dtnbp1 antikoerper, DTNBP1 antikoerper, dtbp1 antikoerper, dtnbp1a antikoerper, dtnbp1.L antikoerper, dtnbp1.S antikoerper, dtnbp1 antikoerper, Dysb antikoerper, dtnbp1b antikoerper

Hintergrund: DTNBP1(Dystrobrevin binding protein 1)plays a role in the biogenesis of lysosome-related organelles such as platelet dense granule and melanosomes. Dystrobrevin binding protein 1 binds to alpha and beta dystrobrevins that are components of the dystrophin-associated protein complex (DPC). It interacts with pallidin and MUTED. Dystrobrevin binding protein 1 is a part of the biogenesis of lysosome-related organelles complex 1 (BLOC-1). Defects in DTNBP1 are the cause of Hermansky-Pudlak syndrome 7 (HPS7). Hermansky-Pudlak syndrome (HPS) is a genetically heterogeneous, rare, autosomal recessive disorder characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS. Dystrobrevin binding protein 1 belongs to the dysbindin family.

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling