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Daf-2 Antikörper (C-Term)

DAF2 Reaktivität: C. elegans IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN965970
  • Target Alle Daf-2 (DAF2) Antikörper anzeigen
    Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))
    Bindungsspezifität
    C-Term
    Reaktivität
    C. elegans
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Polyklonal
    Konjugat
    • 1
    Dieser Daf-2 Antikörper ist unkonjugiert
    Applikation
    • 1
    • 1
    Immunohistochemistry (IHC)
    Aufreinigung
    Purified by antigen-specific affinity chromatography.
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Caenorhabditis elegans daf-2(Abnormal dauer formation protein 2)
  • Applikationshinweise
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))
    Andere Bezeichnung
    Daf-2 (DAF2 Produkte)
    Synonyme
    AI323748 antikoerper, Cd55b antikoerper, Daf antikoerper, Daf-TM antikoerper, TM-DAF antikoerper, CD55 molecule, decay accelerating factor for complement B antikoerper, Insulin-like receptor subunit beta antikoerper, Cd55b antikoerper, daf-2 antikoerper
    Hintergrund
    The daf-2 is an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. A C. elegans neurosecretory signaling system regulates whether animals enter the reproductive life cycle or arrest development at the long-lived dauer diapause stage. daf-2, a key gene in the genetic pathway that mediates this endocrine signaling, encodes an insulin receptor family member. Decreases in DAF-2 signaling induce metabolic and developmental changes, as in mammalian metabolic control by the insulin receptor. Decreased DAF-2 signaling also causes an increase in life-span. Lifespan regulation by insulin-like metabolic control is analogous to mammalian longevity enhancement induced by caloric restriction, suggesting a general link between metabolism, diapause, and longevity.
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