M-CSF/CSF1 Antikörper

Produktnummer ABIN965939

Produktdetails anti-M-CSF/CSF1 Antikörper

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser M-CSF/CSF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CSF1 expressed in E. Coli.

Klon: 2D10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-M-CSF/CSF1 Antikörper (ABIN965939)

Price, Choi, Rosenberg, Stanley: "The predominant form of secreted colony stimulating factor-1 is a proteoglycan." in: The Journal of biological chemistry, Vol. 267, Issue 4, pp. 2190-9, (1992) (PubMed).

Sakai, Umeda, Suzuki, Ishimatsu, Shikita: "Macrophage colony-stimulating factor purified from normal human urine. Amino-terminal sequence and amino acid composition." in: FEBS letters, Vol. 222, Issue 2, pp. 341-4, (1987) (PubMed).

Details zu M-CSF/CSF1

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Andere Bezeichnung: CSF1 (CSF1 Produkte)

Synonyme: CSF-1 antikoerper, MCSF antikoerper, C87615 antikoerper, Csfm antikoerper, op antikoerper, csf1-1 antikoerper, zgc:172186 antikoerper, CSF1 antikoerper, csf1-2 antikoerper, zgc:158436 antikoerper, colony stimulating factor 1 antikoerper, colony stimulating factor 1 (macrophage) antikoerper, colony stimulating factor 1a (macrophage) antikoerper, macrophage colony-stimulating factor 1 antikoerper, macrophage colony stimulating factor antikoerper, colony stimulating factor 1b (macrophage) antikoerper, CSF1 antikoerper, Csf1 antikoerper, csf1a antikoerper, LOC396599 antikoerper, LOC100860895 antikoerper, csf1b antikoerper

Hintergrund: CSF1, also known as MCSF, is a four-alpha-helical bundle cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. This protein may be involved in development of the placenta.
Synonyms: MCSF

Molekulargewicht: 60kDa

Gen-ID: 1435

Pathways: RTK Signalweg