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CHD3 Antikörper

CHD3 Reaktivität: Human, Maus WB, IHC, ELISA, IF, FACS Wirt: Maus Monoclonal 2G4 unconjugated
Produktnummer ABIN965879
  • Target Alle CHD3 Antikörper anzeigen
    CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
    Reaktivität
    • 30
    • 21
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 34
    • 13
    • 1
    Maus
    Klonalität
    • 33
    • 15
    Monoklonal
    Konjugat
    • 27
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHD3 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 13
    • 13
    • 12
    • 11
    • 11
    • 9
    • 8
    • 8
    • 7
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human CHD3 expressed in E. Coli.
    Klon
    2G4
    Isotyp
    IgG1
    Top Product
    Discover our top product CHD3 Primärantikörper
  • Applikationshinweise
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Burd, Kinyamu, Miller, Archer: "UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).

    Goehler, Lalowski, Stelzl, Waelter, Stroedicke, Worm, Droege, Lindenberg, Knoblich, Haenig, Herbst, Suopanki, Scherzinger, Abraham, Bauer, Hasenbank, Fritzsche, Ludewig, Büssow, Buessow, Coleman et al.: "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. ..." in: Molecular cell, Vol. 15, Issue 6, pp. 853-65, (2004) (PubMed).

    Lepesheva, Virus, Waterman: "Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function." in: Biochemistry, Vol. 42, Issue 30, pp. 9091-101, (2003) (PubMed).

  • Target
    CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
    Andere Bezeichnung
    CHD3 (CHD3 Produkte)
    Synonyme
    CG9594 antikoerper, CHD-3 antikoerper, CHD3 antikoerper, DmCHD3 antikoerper, Dmel\\CG9594 antikoerper, chd3 antikoerper, dCHD3 antikoerper, LOC568230 antikoerper, zfh antikoerper, mi-2a antikoerper, mi2-alpha antikoerper, Mi-2a antikoerper, Mi2-ALPHA antikoerper, ZFH antikoerper, 2600010P09Rik antikoerper, AF020312 antikoerper, Chd7 antikoerper, Prp7 antikoerper, Prp9-1 antikoerper, CG9594 gene product from transcript CG9594-RA antikoerper, chromodomain helicase DNA binding protein 3 antikoerper, chromodomain-helicase-DNA-binding protein 3 antikoerper, Chd3 antikoerper, CHD3 antikoerper, chd3 antikoerper, LOC100480350 antikoerper
    Hintergrund
    This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
    Synonyms: ZFH, Mi-2a, Mi2ALPHA, CHD3
    Molekulargewicht
    226kDa
    Gen-ID
    1107
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