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Calpain 3 Antikörper (C-Term)

CAPN3 Reaktivität: Human IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN965743
  • Target Alle Calpain 3 (CAPN3) Antikörper anzeigen
    Calpain 3 (CAPN3)
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 26
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 25
    • 2
    Kaninchen
    Klonalität
    • 25
    • 2
    Polyklonal
    Konjugat
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Calpain 3 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    Aufreinigung
    Purified by antigen-specific affinity chromatography.
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human CAPN3(Calpain-3)
    Top Product
    Discover our top product CAPN3 Primärantikörper
  • Applikationshinweise
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    Calpain 3 (CAPN3)
    Andere Bezeichnung
    CAPN3 (CAPN3 Produkte)
    Synonyme
    capn3 antikoerper, MGC80925 antikoerper, zgc:92687 antikoerper, CAPN3 antikoerper, AI323605 antikoerper, Capa-3 antikoerper, Capa3 antikoerper, Lp82 antikoerper, p94 antikoerper, Lp84 antikoerper, Lp85 antikoerper, CANP3 antikoerper, CANPL3 antikoerper, LGMD2 antikoerper, LGMD2A antikoerper, nCL-1 antikoerper, SKM-CALP antikoerper, SKM-CALPOV antikoerper, nCL1 antikoerper, calpain 1, (mu/I) large subunit L homeolog antikoerper, calpain 3a, (p94) antikoerper, calpain 3 antikoerper, capn1.L antikoerper, capn3a antikoerper, CAPN3 antikoerper, Capn3 antikoerper
    Hintergrund
    CAPN3(Calpain-3) is a calcium-regulated non-lysosomal thiol-protease. It has a broad endopeptidase specificity. CAPN3 is activated by micromolar concentrations of calcium and inhibited by calpastatin. It interacts with TTN/titin. Isoform I is skeletal muscle specific. Defects in CAPN3 are the cause of limb-girdle muscular dystrophy type 2A (LGMD2A). LGMD2A is both autosomal dominantly and recessively transmitted. It is characterized by progressive symmetrical atrophy and weakness of the proximal limb muscles and elevated serum creatine kinase. CAPN3 belongs to the peptidase C2 family and contains 1 calpain catalytic domain and 4 EF-hand domains.
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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