C-JUN Antikörper

Produktnummer ABIN965724

Produktdetails anti-C-JUN Antikörper

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C-JUN Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Spezifität: C-Jun ( Ab-63) antibody detects endogenous levels of c-Jun protein around serine 63.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of serine 63 (L-T-SP-P-D).

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-C-JUN Antikörper (ABIN965724)

Wei, Jin, Schlisio, Harper, Kaelin: "The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase." in: Cancer cell, Vol. 8, Issue 1, pp. 25-33, (2005) (PubMed).

Sevilla, Santos, Barcia, Vega, Lazo: "c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK)." in: Oncogene, Vol. 23, Issue 55, pp. 8950-8, (2004) (PubMed).

Li, Feng, Porter: "JNK-dependent phosphorylation of c-Jun on serine 63 mediates nitric oxide-induced apoptosis of neuroblastoma cells." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4058-65, (2004) (PubMed).

Hurd, Waldron, Rozengurt: "Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminus." in: Oncogene, Vol. 21, Issue 14, pp. 2154-60, (2002) (PubMed).

Details zu C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Andere Bezeichnung: c-Jun (JUN Produkte)

Synonyme: AP-1 antikoerper, AP1 antikoerper, c-Jun antikoerper, fj36h07 antikoerper, wu:fj36h07 antikoerper, zgc:65863 antikoerper, Junc antikoerper, c-jun antikoerper, CG2275 antikoerper, D-Jun antikoerper, D-jun antikoerper, D-jun/Jra antikoerper, DJUN antikoerper, DJun antikoerper, Djun antikoerper, Dmel\\CG2275 antikoerper, JRA antikoerper, JUN antikoerper, Jun antikoerper, V antikoerper, cJun antikoerper, d-JRA antikoerper, d-Jun antikoerper, d-jun antikoerper, dAP-1 antikoerper, dJRA antikoerper, dJUN antikoerper, dJra antikoerper, dJun antikoerper, djun antikoerper, dm-Jun antikoerper, jra antikoerper, jun antikoerper, l(2)46Ef antikoerper, l(2)IA109 antikoerper, l(2R)IA109 antikoerper, Jun proto-oncogene, AP-1 transcription factor subunit antikoerper, jun proto-oncogene S homeolog antikoerper, jun proto-oncogene antikoerper, Jun-related antigen antikoerper, jun proto-oncogene L homeolog antikoerper, JUN antikoerper, Jun antikoerper, jun.S antikoerper, jun antikoerper, Jra antikoerper, jun.L antikoerper

Pathways: MAPK Signalweg, RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteine