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BIM Antikörper

BCL2L11 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN965669
  • Target Alle BIM (BCL2L11) Antikörper anzeigen
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    Reaktivität
    • 179
    • 101
    • 91
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 167
    • 9
    • 5
    • 1
    Kaninchen
    Klonalität
    • 152
    • 30
    Polyklonal
    Konjugat
    • 69
    • 16
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BIM Antikörper ist unkonjugiert
    Applikation
    • 124
    • 65
    • 51
    • 28
    • 25
    • 22
    • 15
    • 14
    • 14
    • 13
    • 10
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Spezifität
    BIM (Ab-69/65) antibody detects endogenous levels of total BIM protein.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    The antiserum was produced against synthesized non-phosphopeptide derived from mouse BIM around the phosphorylation site of serine 69 (P-A-SP-P-G).
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  • Applikationshinweise
    IHC: 1:50-1:100.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Fukazawa, Noguchi, Masumi, Murakami, Uehara: "BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors." in: Molecular cancer therapeutics, Vol. 3, Issue 10, pp. 1281-8, (2004) (PubMed).

    Luciano, Jacquel, Colosetti, Herrant, Cagnol, Pages, Auberger: "Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function." in: Oncogene, Vol. 22, Issue 43, pp. 6785-93, (2003) (PubMed).

  • Target
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    Andere Bezeichnung
    BIM (BCL2L11 Produkte)
    Synonyme
    bim antikoerper, BAM antikoerper, BIM antikoerper, BOD antikoerper, 1500006F24Rik antikoerper, Bim antikoerper, Bod antikoerper, BimL antikoerper, BIMEL antikoerper, BCL2-like 11 antikoerper, BCL2 like 11 antikoerper, BCL2-like 11 (apoptosis facilitator) antikoerper, bcl2l11 antikoerper, BCL2L11 antikoerper, Bcl2l11 antikoerper
    Pathways
    PI3K-Akt Signalweg, Neurotrophin Signalübertragung, Tube Formation, Positive Regulation of Endopeptidase Activity
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