Aurora Kinase B Antikörper

Produktnummer ABIN965626

Produktdetails anti-Aurora Kinase B Antikörper

Target: Aurora Kinase B (AURKB)

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser Aurora Kinase B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Ni-NTA purified truncated recombinant AURKB expressed in E. Coli strain BL21 (DE3)

Aufreinigung: Crude ascites.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Referenzen für anti-Aurora Kinase B Antikörper (ABIN965626)

Song, So, Cheng, Tang, Croft: "Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion." in: Immunity, Vol. 22, Issue 5, pp. 621-31, (2005) (PubMed).

Kapoor, Lavoie, Frappier: "EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases." in: Molecular and cellular biology, Vol. 25, Issue 12, pp. 4934-45, (2005) (PubMed).

Details zu Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Andere Bezeichnung: AURKB (AURKB Produkte)

Synonyme: AIK2 antikoerper, AIM-1 antikoerper, AIM1 antikoerper, ARK2 antikoerper, AurB antikoerper, IPL1 antikoerper, PPP1R48 antikoerper, STK12 antikoerper, STK5 antikoerper, aurkb-sv1 antikoerper, aurkb-sv2 antikoerper, AIRK2 antikoerper, AL022959 antikoerper, Aik2 antikoerper, Aim1 antikoerper, Ark2 antikoerper, STK-1 antikoerper, Stk12 antikoerper, Stk5 antikoerper, Aur B antikoerper, Aurora B antikoerper, Aurora-B antikoerper, CG6620 antikoerper, DmAIRK2 antikoerper, DmAurB antikoerper, DmAuroraB antikoerper, Dmel\\CG6620 antikoerper, IAL antikoerper, IAL1 antikoerper, Ial antikoerper, aurB antikoerper, aurora B antikoerper, ARK-2 antikoerper, XAIRK2 antikoerper, aik2 antikoerper, aim-1 antikoerper, aim1 antikoerper, airk2 antikoerper, ark2 antikoerper, ipl1 antikoerper, stk12 antikoerper, stk5 antikoerper, CHUNP6896 antikoerper, fa09g06 antikoerper, stka antikoerper, wu:fa09g06 antikoerper, aurkb antikoerper, AIRK2-B antikoerper, XAIRK2-B antikoerper, aurkb-a antikoerper, aurkb-b antikoerper, xAurora-B-B antikoerper, aurora kinase B antikoerper, aurora B antikoerper, aurora kinase B S homeolog antikoerper, AURKB antikoerper, Aurkb antikoerper, aurB antikoerper, aurkb antikoerper, aurkb.S antikoerper

Hintergrund: AURKB (aurora kinase B, AIK2 or aurora-B), with 344amino acid protein(about 39kDa),localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis. It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2 transcripts arepresent at high levels in human thymus and fetal liver.ARK-2 protein levels are maximal during both S and G2/M phases

Gen-ID: 9212

Pathways: T-Zell Rezeptor Signalweg, Zellzyklus, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades