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PNPLA2 Antikörper (C-Term)

PNPLA2 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN965617
  • Target Alle PNPLA2 Antikörper anzeigen
    PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))
    Bindungsspezifität
    • 16
    • 12
    • 11
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 58
    • 54
    • 11
    • 1
    Human, Maus, Ratte
    Wirt
    • 69
    • 5
    • 3
    • 2
    • 1
    Kaninchen
    Klonalität
    • 75
    • 5
    Polyklonal
    Konjugat
    • 38
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser PNPLA2 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 30
    • 15
    • 14
    • 13
    • 13
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Aufreinigung
    Purified by antigen-specific affinity chromatography.
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ATGL(adipose triglyceride lipase)
    Top Product
    Discover our top product PNPLA2 Primärantikörper
  • Applikationshinweise
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))
    Andere Bezeichnung
    ATGL (adipose triglyceride lipase) (PNPLA2 Produkte)
    Synonyme
    1110001C14Rik antikoerper, ATGL antikoerper, PEDF-R antikoerper, TTS-2.2 antikoerper, TTS2 antikoerper, iPLA2zeta antikoerper, PNPLA2 antikoerper, pnpla2 antikoerper, 0610039C21Rik antikoerper, Atgl antikoerper, RGD1309044 antikoerper, patatin like phospholipase domain containing 2 antikoerper, patatin-like phospholipase domain containing 2 antikoerper, PNPLA2 antikoerper, pnpla2 antikoerper, Pnpla2 antikoerper
    Hintergrund
    ATGL(adipose triglyceride lipase) may function as a lipase and play a role in the adaptive response to a low energy state, such as fasting, by providing fatty acids to other tissues for oxidation. In addition, decreased expression of desnutrin in obesity models suggests its possible contribution to the pathophysiology of obesity. The adipose triglyceride lipase (ATGL) catalyzes the initial step in triglyceride hydrolysis. ATGL contains a patatin domain common to plant acyl-hydrolases. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammals. The iPLA2epsilon (adiponutrin), iPLA2zeta (TTS2.2), and iPLA2eta (GS2) are three novel TAG lipases/acylglycerol transacylases that likely participate in TAG hydrolysis and the acyl-CoA independent transacylation of acylglycerols
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