ARL6 Antikörper (N-Term)

Produktnummer ABIN965594

Produktdetails anti-ARL6 Antikörper

Target: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ARL6 (ADP-ribosylation factorlike protein 6)

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-ARL6 Antikörper (ABIN965594)

Chiang, Nishimura, Searby, Elbedour, Carmi, Ferguson, Secrist, Braun, Casavant, Stone, Sheffield: "Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3)." in: American journal of human genetics, Vol. 75, Issue 3, pp. 475-84, (2004) (PubMed).

Fan, Esmail, Ansley, Blacque, Boroevich, Ross, Moore, Badano, May-Simera, Compton, Green, Lewis, van Haelst, Parfrey, Baillie, Beales, Katsanis, Davidson, Leroux: "Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome." in: Nature genetics, Vol. 36, Issue 9, pp. 989-93, (2004) (PubMed).

Ingley, Williams, Walker, Tsai, Colley, Sayer, Tilbrook, Sarna, Beaumont, Klinken: "A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit." in: FEBS letters, Vol. 459, Issue 1, pp. 69-74, (1999) (PubMed).

Jacobs, Schilf, Fliegert, Koling, Weber, Schürmann, Joost: "ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal." in: FEBS letters, Vol. 456, Issue 3, pp. 384-8, (1999) (PubMed).

Details zu ARL6

Target: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Andere Bezeichnung: ARL6 (ARL6 Produkte)

Synonyme: BBS3 antikoerper, RP55 antikoerper, 1110018H24Rik antikoerper, 2210411E14Rik antikoerper, zgc:101762 antikoerper, arl6 antikoerper, ADP ribosylation factor like GTPase 6 antikoerper, ADP-ribosylation factor-like 6 antikoerper, ADP-ribosylation factor like GTPase 6 antikoerper, ADP-ribosylation factor-like protein 6 antikoerper, ADP ribosylation factor like GTPase 6 L homeolog antikoerper, ARL6 antikoerper, Arl6 antikoerper, arl6 antikoerper, arl-6 antikoerper, arl6.L antikoerper

Hintergrund: ARL6 (ADP-ribosylation factor-like protein 6) belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.