RUNX1T1 Antikörper
(1 reference)Kurzübersicht für RUNX1T1 Antikörper (ABIN965546)
Target
Alle RUNX1T1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Purified by antigen-specific affinity chromatography.
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Immunogen
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human AML1-MTG8(acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c)
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anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Internal Region), (N-Term) antibody
RUNX1T1 Reaktivität: Human ELISA, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibodyRUNX1T1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 5A12 unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Internal Region) antibodyRUNX1T1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibodyRUNX1T1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 1-577) antibodyRUNX1T1 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 335-510) antibodyRUNX1T1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, IP, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 100-390) antibodyRUNX1T1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (N-Term) antibodyRUNX1T1 Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Schwein, Huhn, Affe, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 288-337) antibodyRUNX1T1 Reaktivität: Human, Ratte, Hund, Kaninchen, Schwein, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 221-270) antibodyRUNX1T1 Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd, Schwein, Huhn, Affe, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- ELISA, Western blotting: 1µg/ml for 2hrs.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- This antibody is stored in PBS, 50% glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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: "The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells." in: BMC cancer, Vol. 4, pp. 44, (2004) (PubMed).
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- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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Andere Bezeichnung
- AML1-MTG8
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Hintergrund
- AML1-MTG8(acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c) is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.
Target
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