ADIPOQ Antikörper (N-Term)

Produktnummer ABIN965514

Produktdetails anti-ADIPOQ Antikörper

Target: ADIPOQ (Adiponectin (ADIPOQ))

Bindungsspezifität: AA 55-69, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADIPOQ Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to residues 55-69 of human ADIPOQ(Adiponectin precursor)

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-ADIPOQ Antikörper (ABIN965514)

Arita, Kihara, Ouchi, Takahashi, Maeda, Miyagawa, Hotta, Shimomura, Nakamura, Miyaoka, Kuriyama, Nishida, Yamashita, Okubo, Matsubara, Muraguchi, Ohmoto, Funahashi, Matsuzawa: "Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity." in: Biochemical and biophysical research communications, Vol. 257, Issue 1, pp. 79-83, (1999) (PubMed).

Saito, Tobe, Minoshima, Asakawa, Sumiya, Yoda, Nakano, Shimizu, Tomita: "Organization of the gene for gelatin-binding protein (GBP28)." in: Gene, Vol. 229, Issue 1-2, pp. 67-73, (1999) (PubMed).

Schäffler, Orsó, Palitzsch, Büchler, Drobnik, Fürst, Schölmerich, Schmitz et al.: "The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for ..." in: Biochemical and biophysical research communications, Vol. 260, Issue 2, pp. 416-25, (1999) (PubMed).

Details zu ADIPOQ

Target: ADIPOQ (Adiponectin (ADIPOQ))

Andere Bezeichnung: ADIPOQ (ADIPOQ Produkte)

Synonyme: ADP antikoerper, DCAF9 antikoerper, 6720489L24Rik antikoerper, 9330209L04Rik antikoerper, Adp antikoerper, Mamdc1 antikoerper, RNSVSP4U antikoerper, SVSIV1 antikoerper, Svp4 antikoerper, ACDC antikoerper, ACRP30 antikoerper, ADIPQTL1 antikoerper, ADPN antikoerper, APM-1 antikoerper, APM1 antikoerper, GBP28 antikoerper, apM-1 antikoerper, 30kDa antikoerper, APN antikoerper, Acdc antikoerper, Acrp30 antikoerper, Ad antikoerper, adipo antikoerper, apM1 antikoerper, ADN antikoerper, acrpl antikoerper, adipo-b antikoerper, adipoql antikoerper, zgc:153584 antikoerper, adipoq antikoerper, WD and tetratricopeptide repeats 1 antikoerper, MAM domain containing glycosylphosphatidylinositol anchor 2 antikoerper, seminal vesicle secretory protein 4 antikoerper, adiponectin, C1Q and collagen domain containing antikoerper, adiponectin, C1Q and collagen domain containing, b antikoerper, adiponectin, C1Q and collagen domain containing L homeolog antikoerper, WDTC1 antikoerper, Mdga2 antikoerper, Svs4 antikoerper, ADIPOQ antikoerper, Adipoq antikoerper, adipoqb antikoerper, adipoq.L antikoerper

Hintergrund: ADIPOQ (Adiponectin) is an important negative regulator in hematopoiesis and immunesystems. ADIPOQ may be involved in ending inflammatory responses through its inhibitory functions. ADIPOQ inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. It inhibits TNF-alpha-induced expression of endothelial adhesion molecules. ADIPOQ is involved in the control of fat metabolism and insulin sensitivity. Defects in ADIPOQ are the cause of adiponectin deficiency. The result is a very low concentration of plasma adiponectin. The decreased adiponectin plasma levels are associated with obesity insulin resistance, and diabetes type 2.