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alpha 2 Macroglobulin Antikörper (C-Term)

A2M Reaktivität: Human IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN965491
  • Target Alle alpha 2 Macroglobulin (A2M) Antikörper anzeigen
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    Bindungsspezifität
    • 13
    • 11
    • 9
    • 8
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 108
    • 23
    • 20
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 106
    • 18
    • 15
    • 6
    • 1
    • 1
    Kaninchen
    Klonalität
    • 123
    • 22
    Polyklonal
    Konjugat
    • 77
    • 21
    • 14
    • 9
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser alpha 2 Macroglobulin Antikörper ist unkonjugiert
    Applikation
    • 90
    • 59
    • 37
    • 19
    • 14
    • 9
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC)
    Aufreinigung
    Purified by antigen-specific affinity chromatography.
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human A2M (Alpha-2-macroglobulin precursor)
    Top Product
    Discover our top product A2M Primärantikörper
  • Applikationshinweise
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Bishop, Bell: "Assembly of the endoplasmic reticulum phospholipid bilayer: the phosphatidylcholine transporter." in: Cell, Vol. 42, Issue 1, pp. 51-60, (1985) (PubMed).

  • Target
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    Andere Bezeichnung
    A2M (A2M Produkte)
    Synonyme
    A2MD antikoerper, CPAMD5 antikoerper, FWP007 antikoerper, S863-7 antikoerper, A2MAC1 antikoerper, A2m1 antikoerper, A2maa antikoerper, Mam antikoerper, A2mp antikoerper, A2M antikoerper, LOC733429 antikoerper, endod antikoerper, cpamd5 antikoerper, fwp007 antikoerper, s863-7 antikoerper, a2mb antikoerper, endodermin antikoerper, Alpha-2-M antikoerper, alpha-2-macroglobulin antikoerper, pregnancy-zone protein L homeolog antikoerper, alpha-2-macroglobulin S homeolog antikoerper, pregnancy zone protein antikoerper, alpha-2-macroglobulin-like antikoerper, A2M antikoerper, A2m antikoerper, LOC477699 antikoerper, pzp.L antikoerper, AZL_c00450 antikoerper, LOC100349077 antikoerper, a2m antikoerper, LOC100061656 antikoerper, LOC100090399 antikoerper, a2m.S antikoerper, LOC100469973 antikoerper, LOC100595735 antikoerper, PZP antikoerper, LOC100353095 antikoerper, LOC101122940 antikoerper, LOC101801552 antikoerper, LOC100911545 antikoerper
    Hintergrund
    A2M(Alpha-2-macroglobulin is able to inhibit all four classes of proteinases by a unique trapping mechanism. This protein has a peptide stretch, called the `bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
    Pathways
    Lipid Metabolism
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