Cadherin Antikörper

Antigen: Cadherin

Synonyme: PCDH10, OLpcad, cadherin, ci-cadherin

Klonalität: Monoklonal (67A4)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (IHC)

Produktnummer: ABIN95840

Produktbeschreibung

Immunogen: BALB/C mice were injected with human breast carcinoma cell line T471.

Format: Supernatant

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 67A4

Spezifität: This antibody is specific to E-cadherin of 123 kD molecule of the cadherin family. E-cadherin is expressed on non-neuronal epithelial cells. This antibody reacts with tumor cell lines such as breast carcinoma cells.

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Positive Control: Tonsil. Cellular localization: Cell membrane Other Applications: Immunoprecipitation, Western blotting (1:100).

Konzentration: 100ug/ml approximately

Buffer: This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Forschungsgebiet: Extrazelluläre Matrix, Signaltransduktion, Zytoskelett

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Publikationen

Publikationen: Geiger, Ayalon: "Cadherins." in: Annual review of cell biology, Vol. 8, pp. 307-32, 1993 (PubMed).

Nagafuchi, Shirayoshi, Okazaki et al.: "Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA." in: Nature, Vol. 329, Issue 6137, pp. 341-3, 1987 (PubMed).