XDH Antikörper (N-Term)

Produktnummer ABIN955594

Produktdetails anti-XDH Antikörper

Target: XDH (Xanthine Dehydrogenase (XDH))

Bindungsspezifität: AA 213-242, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects Xanthine dehydrogenase/oxidase (N-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse.

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 213~242 amino acids from the N-terminal region of human XDH

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Referenzen für anti-XDH Antikörper (ABIN955594)

Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

Details zu XDH

Target: XDH (Xanthine Dehydrogenase (XDH))

Andere Bezeichnung: XDH (XDH Produkte)

Synonyme: XO antikoerper, XOR antikoerper, Xor antikoerper, Xox-1 antikoerper, Xox1 antikoerper, XDH antikoerper, im:7146167 antikoerper, DDBDRAFT_0219626 antikoerper, DDBDRAFT_0230176 antikoerper, DDB_0219626 antikoerper, DDB_0230176 antikoerper, xanthine dehydrogenase antikoerper, xanthine dehydrogenase/oxidase antikoerper, Xanthine dehydrogenase antikoerper, XDH antikoerper, Xdh antikoerper, xdh antikoerper, LOC576712 antikoerper, Trebr_1754 antikoerper

Hintergrund: XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.Synonyms: Xanthine dehydrogenase/oxidase

Gen-ID: 7498

NCBI Accession: NP_000370

Pathways: Positive Regulation of Endopeptidase Activity