Vitamin D Receptor Antikörper (Middle Region)

Produktnummer ABIN955519

Produktdetails anti-Vitamin D Receptor Antikörper

Target: Vitamin D Receptor (VDR)

Bindungsspezifität: AA 273-299, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vitamin D Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects Vitamin D3 receptor / NR1I1 (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 273-299 amino acids from the Central region of human VDR

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu Vitamin D Receptor

Target: Vitamin D Receptor (VDR)

Andere Bezeichnung: Vitamin D3 Receptor / NR1I1 (VDR Produkte)

Synonyme: vdrbeta antikoerper, vdr0 antikoerper, LOC100136219 antikoerper, NR1I1-B antikoerper, gb:dq017633 antikoerper, vdr-b antikoerper, Ci-VDR-b antikoerper, VDR antikoerper, LOC100221284 antikoerper, vdr-A antikoerper, xVDR antikoerper, Nr1i1 antikoerper, vdr antikoerper, NR1I1 antikoerper, PPP1R163 antikoerper, vitamin D (1,25- dihydroxyvitamin D3) receptor antikoerper, vitamin D receptor antikoerper, vitamin D3 receptor A antikoerper, vitamin D receptor b antikoerper, nuclear receptor VDR-b antikoerper, vitamin D (1,25- dihydroxyvitamin D3) receptor L homeolog antikoerper, vitamin D (1,25-dihydroxyvitamin D3) receptor antikoerper, vitamin D receptor a antikoerper, vdr antikoerper, vdr0 antikoerper, VDR antikoerper, LOC100136219 antikoerper, vdrb antikoerper, vdr-b antikoerper, vdr.L antikoerper, Vdr antikoerper, vdra antikoerper

Substanzklasse: Chemical

Hintergrund: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.Synonyms: 1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR

Gen-ID: 7421

NCBI Accession: NP_000367

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway