USP12 Antikörper (Ubiquitin Specific Peptidase 12) (AA 221-251)

Details for Product anti-USP12 Antibody No. ABIN955485, Anbieter: Anmelden zum Anzeigen
Antigen
  • hapln3
  • USP12P1
  • usp12
  • Ubh1
  • ubh1
  • usp12l1
  • UBH1
  • USP12L1
  • USP12
  • sb:eu882
  • wu:fi09d12
  • ubiquitin specific peptidase 12
  • Ubiquitin carboxyl-terminal hydrolase 12
  • ubiquitin specific peptidase 12 pseudogene 1
  • ubiquitin specific peptidase 12a
  • usp12
  • USP12
  • ubp12
  • Usp12
  • usp12-a
  • USP12P1
  • usp12a
Epitop
AA 221-251, Middle Region
18
14
9
8
8
7
4
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus
57
36
9
4
4
4
4
3
3
2
1
1
1
1
Wirt
Kaninchen
64
8
Klonalität
Polyklonal
Konjugat
Dieser USP12 Antikörper ist unkonjugiert
6
6
6
6
6
6
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
68
49
17
3
2
Optionen
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Immunogen KLH conjugated synthetic peptide between 221-251 amino acids from the Central region of human USP12
Isotyp Ig
Spezifität This antibody detects USP12 (Center).
Kreuzreaktivität (Details) Species reactivity (expected):Bovine, Xenopus.
Species reactivity (tested):Human, Mouse.
Reinigung Protein A column followed by peptide affinity purification
Andere Bezeichnung USP12 (USP12 Antibody Abstract)
Hintergrund USP12is a deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.Synonyms: Deubiquitinating enzyme 12, UBH1, USP12L1, Ubiquitin carboxyl-terminal hydrolase 12, Ubiquitin thioesterase 12, Ubiquitin-hydrolyzing enzyme 1, Ubiquitin-specific-processing protease 12
Gen-ID 219333
NCBI Accession NP_872294
Forschungsgebiet Proteolysis / Ubiquitin
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Western Blotting (WB) image for anti-USP12 Antikörper (Ubiquitin Specific Peptidase 12) (AA 221-251) (ABIN955485) USP12 Antibody (Center) western blot analysis in A375 cell line lysates (35 µg/lane)....
Western Blotting (WB) image for anti-USP12 Antikörper (Ubiquitin Specific Peptidase 12) (AA 221-251) (ABIN955485) USP12 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35 µg/...
Allgemeine Veröffentlichungen Kee, Yang, Cohn, Haas, Gygi, DAndrea: "WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex." in: The Journal of biological chemistry, Vol. 285, Issue 15, pp. 11252-7, 2010 (PubMed).

Cohn, Kee, Haas, Gygi, DAndrea: "UAF1 is a subunit of multiple deubiquitinating enzyme complexes." in: The Journal of biological chemistry, Vol. 284, Issue 8, pp. 5343-51, 2009 (PubMed).

Asano, Matsushita, Umeno, Hosono, Takahashi, Kawaguchi, Matsumoto, Matsui, Kakuta, Kinouchi, Shimosegawa, Hosokawa, Arimura, Shinomura, Kiyohara, Tsunoda, Kamatani, Iida, Nakamura, Kubo: "A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population." in: Nature genetics, Vol. 41, Issue 12, pp. 1325-9, 2009 (PubMed).

Dunham, Matthews, Burton, Ashurst, Howe, Ashcroft, Beare, Burford, Hunt, Griffiths-Jones, Jones, Keenan, Oliver, Scott, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey et al.: "The DNA sequence and analysis of human chromosome 13. ..." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).

Puente, Sánchez, Overall, López-Otín: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, 2003 (PubMed).