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Ubiquitin Specific Peptidase 12 (USP12) (AA 221-251), (Middle Region) Antikörper

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Synonyme hapln3, USP12P1, usp12, Ubh1, ubh1, usp12l1, UBH1, USP12L1, USP12, sb:eu882, wu:fi09d12
Epitop
AA 221-251, Middle Region
(21), (15), (15), (14), (9), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Reaktivität
Human, Maus
(56), (26), (6), (1), (1), (1), (1), (1)
Wirt
Kaninchen
(65), (7)
Klonalität
Polyklonal
Konjugat
Unkonjugiert
(6), (6), (6), (6), (6), (6)
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
(65), (49), (16), (3), (2)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen Neu
Produkt-ID vom Hersteller Anmelden zum Anzeigen Neu
Menge 0.4 mL
Lieferung nach Deutschland ( )
Verfügbarkeit Lieferung in 8 bis 10 Werktagen
Immunogen KLH conjugated synthetic peptide between 221-251 amino acids from the Central region of human USP12
Isotyp Ig
Spezifität This antibody detects USP12 (Center).
Kreuzreaktivität (Details) Species reactivity (expected):Bovine, Xenopus.
Species reactivity (tested):Human, Mouse.
Reinigung Protein A column followed by peptide affinity purification
Andere Bezeichnung USP12 (USP12 Antibody Abstract)
Hintergrund USP12is a deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.Synonyms: Deubiquitinating enzyme 12, UBH1, USP12L1, Ubiquitin carboxyl-terminal hydrolase 12, Ubiquitin thioesterase 12, Ubiquitin-hydrolyzing enzyme 1, Ubiquitin-specific-processing protease 12
Gen-ID 219333
NCBI Accession NP_872294
Forschungsgebiet Proteolysis / Ubiquitin
Pathways
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Western Blotting (WB) image for anti-Ubiquitin Specific Peptidase 12 (USP12) (AA 221-251), (Middle Region) Antikörper (ABIN955485) USP12 Antibody (Center) western blot analysis in A375 cell line lysates (35 µg/lane)....
Western Blotting (WB) image for anti-Ubiquitin Specific Peptidase 12 (USP12) (AA 221-251), (Middle Region) Antikörper (ABIN955485) USP12 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35 µg/...
Allgemeine Veröffentlichungen Kee, Yang, Cohn et al.: "WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex." in: The Journal of biological chemistry, Vol. 285, Issue 15, pp. 11252-7, 2010 (PubMed).

Asano, Matsushita, Umeno et al.: "A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population." in: Nature genetics, Vol. 41, Issue 12, pp. 1325-9, 2009 (PubMed).

Cohn, Kee, Haas et al.: "UAF1 is a subunit of multiple deubiquitinating enzyme complexes." in: The Journal of biological chemistry, Vol. 284, Issue 8, pp. 5343-51, 2009 (PubMed).

Dunham, Matthews, Burton et al.: "The DNA sequence and analysis of human chromosome 13. ..." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).

Puente, Sánchez, Overall et al.: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, 2003 (PubMed).

Produktnummer ABIN955485
418,00 €
Zzgl. Versandkosten 20,00 € und MWSt

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