ULK1 Antikörper

Produktnummer ABIN955448

Produktdetails anti-ULK1 Antikörper

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse Unc-51-like kinase 1 (ULK1).

Aufreinigung: Affinity Chromatography on Proteinn A

Immunogen: KLH conjugated synthetic peptide selected from Human Unc-51-like kinase 1 (ULK1) Genename: ULK1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Andere Bezeichnung: Unc-51-Like Kinase 1 (ULK1) (ULK1 Produkte)

Synonyme: ATG1 antikoerper, ATG1A antikoerper, UNC51 antikoerper, Unc51.1 antikoerper, hATG1 antikoerper, si:dkey-11o18.7 antikoerper, ulk1 antikoerper, ULK1 antikoerper, AU041434 antikoerper, mKIAA0722 antikoerper, zgc:195008 antikoerper, unc-51 like autophagy activating kinase 1 antikoerper, unc-51 like kinase 1 antikoerper, unc-51 like autophagy activating kinase 1a antikoerper, ULK1 antikoerper, Ulk1 antikoerper, ulk1b antikoerper, ulk1a antikoerper

Hintergrund: ULK1 is involved in autophagy. It is required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. It is involved in axon growth (By similarity) and plays an essential role in neurite extension of cerebellar granule cells (By similarity).Synonyms: KIAA0722, Serine/threonine-protein kinase ULK1

Molekulargewicht: 112601 Da

Gen-ID: 8408

NCBI Accession: NP_003556

Pathways: Regulation of Cell Size, Autophagie