Bag-1 (RAP46 Protein) Antikörper

Antigen: Bag-1 (RAP46 Protein)

Klonalität: Monoklonal (3-10G3E2)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p)), Immunpräzipitation (IP), Western Blot (WB)

Produktnummer: ABIN95528

Produktbeschreibung

Immunogen: BALB/C mice were injected with full length recombinant human BAG-1 protein.

Format: Ig-fraction

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 3-10G3E2

Spezifität: This antibody reacts with a 36 kD protein known as BAG-1. BAG-1 is a multifunctional protein, which regulates several cellular processes including cell survival, signal transduction and protein folding. BAG-1 blocks apoptosis and interacts with several types of proteins, including bcl-2 family proteins, the kinase Raf-1, tyrosine kinase growth factor receptors and steroid hormone receptors.

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Positive Control: Breast carcinoma. Cellular localization: Nuclear, cytoplasmic Other Applications: Immunoprecipitation, Western Blotting (1:100-500).

Konzentration: 100ug/ml approximately

Buffer: This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Bilder

Formalin fixed paraffin embedded human breast carcinoma stained with BAG-1 antibody