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STING/TMEM173 Antikörper (C-Term)

TMEM173 Reaktivität: Human, Maus WB, FACS, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN955254
  • Target Alle STING/TMEM173 (TMEM173) Antikörper anzeigen
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Bindungsspezifität
    • 18
    • 15
    • 12
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 318-348, C-Term
    Reaktivität
    • 70
    • 25
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 84
    • 5
    Kaninchen
    Klonalität
    • 73
    • 16
    Polyklonal
    Konjugat
    • 41
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STING/TMEM173 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 32
    • 24
    • 21
    • 13
    • 13
    • 12
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects TMEM173 / STING (C-term).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse
    Aufreinigung
    Protein A column followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 318~348 amino acids from the C-terminal region of human TM173
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TMEM173 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • Target
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Andere Bezeichnung
    TMEM173 / STING (TMEM173 Produkte)
    Synonyme
    ERIS antikoerper, MITA antikoerper, MPYS antikoerper, NET23 antikoerper, STING antikoerper, 2610307O08Rik antikoerper, Mita antikoerper, RGD1562552 antikoerper, transmembrane protein 173 antikoerper, TMEM173 antikoerper, Tmem173 antikoerper
    Hintergrund
    Acts as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.Synonyms: MITA, Mediator of IRF3 activation, Stimulator of interferon genes protein, Transmembrane protein 173
    Gen-ID
    340061
    NCBI Accession
    NP_938023
    Pathways
    Activation of Innate immune Response
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