STARD5 Antikörper (N-Term)

Produktnummer ABIN954973

Produktdetails anti-STARD5 Antikörper

Target: STARD5 (StAR-Related Lipid Transfer (START) Domain Containing 5 (STARD5))

Bindungsspezifität: AA 33-63, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STARD5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human STARD5 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 33-63 amino acids from the N-terminal region of human STARD5

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu STARD5

Target: STARD5 (StAR-Related Lipid Transfer (START) Domain Containing 5 (STARD5))

Andere Bezeichnung: STARD5 (STARD5 Produkte)

Synonyme: STARD5 antikoerper, MGC131265 antikoerper, DKFZp469N2125 antikoerper, 2310058G22Rik antikoerper, AI607880 antikoerper, D7Ertd152e antikoerper, RGD1561783 antikoerper, StAR related lipid transfer domain containing 5 antikoerper, StAR related lipid transfer domain containing 5 S homeolog antikoerper, StAR-related lipid transfer (START) domain containing 5 antikoerper, StAR-related lipid transfer domain containing 5 antikoerper, STARD5 antikoerper, stard5.S antikoerper, Stard5 antikoerper

Hintergrund: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002 [PubMed 12011452]).Synonyms: START domain-containing protein 5, StAR-related lipid transfer protein 5

Molekulargewicht: 23794 Da

Gen-ID: 80765

NCBI Accession: NP_871629

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process