SF3B3 Antikörper (C-Term)

Produktnummer ABIN954757

Produktdetails anti-SF3B3 Antikörper

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Bindungsspezifität: AA 1053-1082, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: Recognizes SF3B3 (C-term).

Aufreinigung: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 1053-1082 amino acids from the C-terminal region of Human SF3B3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SF3B3

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Andere Bezeichnung: SF3B3 / SAP130 (SF3B3 Produkte)

Synonyme: GB11574 antikoerper, rse1 antikoerper, sap130 antikoerper, sf3b130 antikoerper, staf130 antikoerper, sf3b3 antikoerper, 1810061H24Rik antikoerper, 5730409A01Rik antikoerper, AA409318 antikoerper, D8Ertd633e antikoerper, RSE1 antikoerper, SAP130 antikoerper, mKIAA0017 antikoerper, ik:tdsubc_2b2 antikoerper, wu:fb81f05 antikoerper, xx:tdsubc_2b2 antikoerper, zgc:55440 antikoerper, SF3b130 antikoerper, STAF130 antikoerper, splicing factor 3b subunit 3 antikoerper, splicing factor 3B subunit 3 antikoerper, splicing factor 3b, subunit 3, 130kDa antikoerper, splicing factor 3b subunit 3 L homeolog antikoerper, splicing factor 3b, subunit 3 antikoerper, SF3B3 antikoerper, LOC550935 antikoerper, sf3b3 antikoerper, Sf3b3 antikoerper, LOC100178056 antikoerper, sf3b3.L antikoerper

Hintergrund: This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.Synonyms: KIAA0017, Pre-mRNA-splicing factor SF3b 130 kDa subunit, SAP 130, SAP-130, SF3b130, STAF130, Spliceosome-associated protein 130, Splicing factor 3B subunit 3

Gen-ID: 23450

NCBI Accession: NP_036558