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PTPRN Antikörper

PTPRN Reaktivität: Human WB, IHC (p), EIA Wirt: Maus Monoclonal 8-00E-003 unconjugated
Produktnummer ABIN954381
  • Target Alle PTPRN Antikörper anzeigen
    PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
    Reaktivität
    • 39
    • 25
    • 10
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 49
    • 6
    • 1
    Maus
    Klonalität
    • 52
    • 4
    Monoklonal
    Konjugat
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PTPRN Antikörper ist unkonjugiert
    Applikation
    • 24
    • 22
    • 18
    • 13
    • 13
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes PTPRN
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Protein A Chromatography
    Immunogen
    Recombinant protein.
    Klon
    8-00E-003
    Isotyp
    IgG2a
    Top Product
    Discover our top product PTPRN Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
    Andere Bezeichnung
    PTPRN (PTPRN Produkte)
    Synonyme
    IA-2 antikoerper, IA-2/PTP antikoerper, IA2 antikoerper, ICA512 antikoerper, R-PTP-N antikoerper, mIA-A antikoerper, mKIAA4064 antikoerper, Ia-2 antikoerper, fc43c04 antikoerper, ptprn antikoerper, wu:fc43c04 antikoerper, ia-2 antikoerper, ia2 antikoerper, ica512 antikoerper, r-ptp-n antikoerper, protein tyrosine phosphatase, receptor type N antikoerper, protein tyrosine phosphatase, receptor type, N antikoerper, protein tyrosine phosphatase, receptor type, Na antikoerper, protein tyrosine phosphatase, receptor type N L homeolog antikoerper, PTPRN antikoerper, Ptprn antikoerper, ptprna antikoerper, ptprn.L antikoerper
    Hintergrund
    IA-2, a R8 receptor protein tyrosine phosphatase, is one of the major autoantigens in type 1 diabetes. Autoantibodies against IA-2 have been detected in large numbers newly diagnosed patients with type 1 diabetes and appear to identify a subgroup of prediabetic subjects who rapidly progress to type 1 diabetes, however, IA-2 polymorphisms do not appear to be associated with type 1 diabetes. Three alternative spliced variants of IA-2 have been documented and alternative splicing of IA-2 gene has been suggested to be a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen.Synonyms: ICA3, ICA512, Islet cell antigen 512, PTP IA-2, R-PTP-N, Receptor-type tyrosine-protein phosphatase-like N
    Gen-ID
    5798
    NCBI Accession
    NP_002837
    UniProt
    Q16849
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