PREX1 Antikörper (Middle Region)

Produktnummer ABIN954296

Produktdetails anti-PREX1 Antikörper

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Bindungsspezifität: AA 573-602, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PREX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to PREX1.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 573~602 amino acids from the Central region of human PREX1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PREX1

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Andere Bezeichnung: PREX1 (PREX1 Produkte)

Synonyme: MGC68772 antikoerper, P-REX1 antikoerper, G630042G04 antikoerper, Setd6 antikoerper, RGD1306534 antikoerper, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog antikoerper, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 antikoerper, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 antikoerper, prex1.L antikoerper, PREX1 antikoerper, prex1 antikoerper, Prex1 antikoerper

Hintergrund: The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.Synonyms: 4, 5)-dependent Rac exchanger 1, 5-trisphosphate-dependent Rac exchanger 1 protein, KIAA1415, P-Rex1, Phosphatidylinositol 3, PtdIns(3

Molekulargewicht: 186203 Da

Gen-ID: 57580

NCBI Accession: NP_065871

Pathways: Regulation of Actin Filament Polymerization