PPP3CC Antikörper (N-Term)

Produktnummer ABIN954277

Produktdetails anti-PPP3CC Antikörper

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Bindungsspezifität: AA 17-45, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP3CC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human PPP3CC / CALNA3 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 17-45 amino acids from the N-terminal region of Human PPP3CC

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PPP3CC

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Andere Bezeichnung: PPP3CC / CALNA3 (PPP3CC Produkte)

Synonyme: CALNA3 antikoerper, CNA3 antikoerper, PP2Bgamma antikoerper, Calnc antikoerper, ppp3cc antikoerper, sb:cb767 antikoerper, si:dkey-21k4.5 antikoerper, calna3 antikoerper, cna3 antikoerper, pp2bgamma antikoerper, im:7163784 antikoerper, zgc:158685 antikoerper, protein phosphatase 3 catalytic subunit gamma antikoerper, protein phosphatase 3, catalytic subunit, gamma isoform antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme, a antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme L homeolog antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme, b antikoerper, PPP3CC antikoerper, Ppp3cc antikoerper, ppp3cca antikoerper, ppp3cc antikoerper, ppp3cc.L antikoerper, ppp3ccb antikoerper

Hintergrund: Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1, MIM 114105), calcineurin A-beta (CALNA2, MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).Synonyms: CAM-PRP catalytic subunit, CNA3, Calcineurin testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, protein phosphatase 2B catalytic subunit gamma

Molekulargewicht: 58129 Da

Gen-ID: 5533

NCBI Accession: NP_005596

Pathways: RTK Signalweg, WNT Signalweg, VEGF Signaling, BCR Signaling