PARP2 Antikörper (C-Term)

Produktnummer ABIN953995

Produktdetails anti-PARP2 Antikörper

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Bindungsspezifität: AA 313-344, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse PARP2 (C-term).

Aufreinigung: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 313-344 amino acids from the C-terminal region of Human PARP2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Andere Bezeichnung: PARP2 (PARP2 Produkte)

Synonyme: ADPRT2 antikoerper, ADPRTL2 antikoerper, ADPRTL3 antikoerper, ARTD2 antikoerper, PARP-2 antikoerper, pADPRT-2 antikoerper, Adprt2 antikoerper, Adprtl2 antikoerper, Aspartl2 antikoerper, C78626 antikoerper, cb996 antikoerper, adprtl2 antikoerper, ADPRT-2 antikoerper, APP antikoerper, ATPARP1 antikoerper, PARP1 antikoerper, POLY(ADP-RIBOSE) POLYMERASE antikoerper, POLY(ADP-RIBOSE) POLYMERASE 1 antikoerper, PP antikoerper, T14P8.19 antikoerper, T14P8_19 antikoerper, poly(ADP-ribose) polymerase antikoerper, poly(ADP-ribose) polymerase 2 antikoerper, poly(ADP-ribose) polymerase 2 antikoerper, poly (ADP-ribose) polymerase family, member 2 antikoerper, poly (ADP-ribose) polymerase 2 antikoerper, poly(ADP-ribose) polymerase 2 S homeolog antikoerper, poly(ADP-ribose) polymerase antikoerper, PARP2 antikoerper, Parp2 antikoerper, parp2 antikoerper, parp2.S antikoerper

Hintergrund: Parp2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.Synonyms: ADPRT2, ADPRTL2, EC=2.4.2.30, NAD(+) ADP-ribosyltransferase 2, PARP 2, PARP-2, Poly [ADP-ribose] polymerase 2, Poly[ADP-ribose] synthetase 2, pADPRT-2

Molekulargewicht: 63397 Da

Gen-ID: 11546

NCBI Accession: NP_033762

Pathways: DNA Reparatur