SPG7 Antikörper (Middle Region)

Produktnummer ABIN953990

Produktdetails anti-SPG7 Antikörper

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Bindungsspezifität: AA 114-141, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPG7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Paraplegin / SPG7.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 114-141aa) of human Paraplegin / SPG7

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SPG7

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Andere Bezeichnung: Paraplegin / SPG7 (SPG7 Produkte)

Synonyme: CAR antikoerper, CMAR antikoerper, PGN antikoerper, SPG5C antikoerper, AI452278 antikoerper, AU015315 antikoerper, Cmar antikoerper, SPG7, paraplegin matrix AAA peptidase subunit antikoerper, SPG7 antikoerper, Spg7 antikoerper

Hintergrund: The SPG7 gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7.Synonyms: CAR, CMAR, PGN, Spastic paraplegia 7 protein

Gen-ID: 6687

NCBI Accession: NP_003110