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MXI1 Antikörper (Middle Region)

MXI1 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN953554
  • Target Alle MXI1 Antikörper anzeigen
    MXI1 (MAX Interactor 1 (MXI1))
    Bindungsspezifität
    • 9
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 52-82, Middle Region
    Reaktivität
    • 34
    • 33
    • 17
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 41
    • 4
    • 2
    Kaninchen
    Klonalität
    • 43
    • 4
    Polyklonal
    Konjugat
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MXI1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 23
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes human and mouse MXI1.
    Aufreinigung
    Purified through a Protein A column followed by peptide affinity purification
    Immunogen
    Synthetic peptide - KLH conjugated - corresponding to the central region (between 52-82aa) of human MXI1.
    Isotyp
    Ig Fraction
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    MXI1 (MAX Interactor 1 (MXI1))
    Andere Bezeichnung
    MXI1 (MXI1 Produkte)
    Synonyme
    mxi antikoerper, mad2 antikoerper, mxd2 antikoerper, xmxi1 antikoerper, MGC89544 antikoerper, MXI1 antikoerper, etID309773.22 antikoerper, fb16b12 antikoerper, fb55f03 antikoerper, wu:fb16b12 antikoerper, wu:fb55f03 antikoerper, wu:fd06a08 antikoerper, wu:fz74f10 antikoerper, ENSMUSG00000067085 antikoerper, Gm10197 antikoerper, Mad2 antikoerper, bHLHc11 antikoerper, MXI-WR antikoerper, MAD2 antikoerper, MXD2 antikoerper, MXI antikoerper, MAX interactor 1, dimerization protein antikoerper, max interactor 1, dimerization protein antikoerper, MAX interactor 1, dimerization protein L homeolog antikoerper, mxi1 antikoerper, MXI1 antikoerper, Mxi1 antikoerper, mxi1.L antikoerper
    Hintergrund
    Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.Synonyms: Class C basic helix-loop-helix protein 11, MAX-interacting protein 1, Max interactor 1, bHLHc11
    Molekulargewicht
    26062 Da
    Gen-ID
    4601
    NCBI Accession
    NP_005953
    Pathways
    Maintenance of Protein Location
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