MED14 Antikörper (Middle Region)

Produktnummer ABIN953367

Produktdetails anti-MED14 Antikörper

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Bindungsspezifität: AA 585-615, Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse MED14 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 585-615 amino acids from the Central region of human MED14

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MED14

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Andere Bezeichnung: MED14 (MED14 Produkte)

Synonyme: CG12031 antikoerper, Dmel\\CG12031 antikoerper, Med14 antikoerper, Trap170 antikoerper, dTRAP170 antikoerper, p160 antikoerper, EXLM1 antikoerper, crsp150 antikoerper, crsp2 antikoerper, trap170 antikoerper, wu:fd21c05 antikoerper, wu:fk28h11 antikoerper, CRSP2 antikoerper, NV18605 antikoerper, CRSP150 antikoerper, CSRP antikoerper, CXorf4 antikoerper, DRIP150 antikoerper, RGR1 antikoerper, TRAP170 antikoerper, 9930001L01Rik antikoerper, AU041628 antikoerper, Crsp2 antikoerper, ENSMUSG00000073278 antikoerper, Gm641 antikoerper, ORF1 antikoerper, RGD1560170 antikoerper, Mediator complex subunit 14 antikoerper, mediator complex subunit 14 antikoerper, mediator of RNA polymerase II transcription subunit 14 antikoerper, transcriptional regulation antikoerper, MED14 antikoerper, med14 antikoerper, LOC100113592 antikoerper, Med14 antikoerper, RGR1 antikoerper

Hintergrund: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.Synonyms: ARC150, Activator-recruited cofactor 150 kDa component, CRSP complex subunit 2, CRSP2, CXorf4, Cofactor required for Sp1 transcriptional activation subunit 2, DRIP150, EXLM1, Mediator of RNA polymerase II transcription subunit 14, RGR1, TRAP170 Mediator complex 14, Thyroid hormone receptor-associated protein complex 170 kDa component, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component

Molekulargewicht: 160607 Da

Gen-ID: 9282

NCBI Accession: NP_004220

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha