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IL12RB2 Antikörper (C-Term)
IL12RB2
Reaktivität: Human
WB, FACS, IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-IL12RB2 Antikörper
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Target
Alle IL12RB2 Antikörper anzeigen
IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Bindungsspezifität
Alle Epitope für IL12RB2 Antikörper
AA 759-788, C-Term
Reaktivität
Alle Reaktivitäten für IL12RB2 Antikörper
Human
Wirt
Alle Wirte für IL12RB2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für IL12RB2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für IL12RB2 Antikörper
Dieser IL12RB2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL12RB2 Antikörper
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
This antibody detects human IL12RB2 at C-term.
Kreuzreaktivität (Details)
Species reactivity (tested):Human
Aufreinigung
Purified through a protein A column; followed by peptide affinity purification.
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 759-788aa) of human IL12RB2.
Isotyp
Ig Fraction
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Discover our top product IL12RB2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu IL12RB2
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Target
IL12RB2
(Interleukin 12 Receptor, beta 2 (IL12RB2))
Andere Bezeichnung
IL12RB2 (IL12RB2 Produkte )
Synonyme
IL12RB2 antikoerper, A930027I18Rik antikoerper, IL-12RB2 antikoerper, Ifnm antikoerper, interleukin 12 receptor subunit beta 2 antikoerper, interleukin 12 receptor, beta 2 antikoerper, IL12RB2 antikoerper, Il12rb2 antikoerper
Hintergrund
The protein encoded by the IL12RB2 gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.Synonyms: IL-12 receptor beta-2, IL-12R-beta-2, Interleukin-12 receptor beta-2 chain
Gen-ID
3595
NCBI Accession
NP_001550
Pathways
JAK-STAT Signalweg
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