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IL12RB2 Antikörper (C-Term)

IL12RB2 Reaktivität: Human WB, FACS, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN952881
  • Target Alle IL12RB2 Antikörper anzeigen
    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
    Bindungsspezifität
    • 15
    • 14
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 759-788, C-Term
    Reaktivität
    • 64
    • 16
    • 8
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 59
    • 10
    • 1
    Kaninchen
    Klonalität
    • 62
    • 8
    Polyklonal
    Konjugat
    • 29
    • 7
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL12RB2 Antikörper ist unkonjugiert
    Applikation
    • 58
    • 25
    • 19
    • 18
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects human IL12RB2 at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Purified through a protein A column; followed by peptide affinity purification.
    Immunogen
    Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 759-788aa) of human IL12RB2.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product IL12RB2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
    Andere Bezeichnung
    IL12RB2 (IL12RB2 Produkte)
    Synonyme
    IL12RB2 antikoerper, A930027I18Rik antikoerper, IL-12RB2 antikoerper, Ifnm antikoerper, interleukin 12 receptor subunit beta 2 antikoerper, interleukin 12 receptor, beta 2 antikoerper, IL12RB2 antikoerper, Il12rb2 antikoerper
    Hintergrund
    The protein encoded by the IL12RB2 gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.Synonyms: IL-12 receptor beta-2, IL-12R-beta-2, Interleukin-12 receptor beta-2 chain
    Gen-ID
    3595
    NCBI Accession
    NP_001550
    Pathways
    JAK-STAT Signalweg
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