FBXW8 Antikörper (Middle Region)

Produktnummer ABIN952296

Produktdetails anti-FBXW8 Antikörper

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Bindungsspezifität: AA 273-303, Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to FBXW8.

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 273-303 amino acids from the Central region of human FBXW8

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FBXW8

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Andere Bezeichnung: FBXW8 (FBXW8 Produkte)

Synonyme: FBW6 antikoerper, FBW8 antikoerper, FBX29 antikoerper, FBXO29 antikoerper, FBXW6 antikoerper, 4930438M06Rik antikoerper, Fbx29 antikoerper, F-box and WD repeat domain containing 8 antikoerper, ring finger protein, transmembrane 2 antikoerper, F-box and WD-40 domain protein 8 antikoerper, FBXW8 antikoerper, Fbxw8 antikoerper, RNFT2 antikoerper

Hintergrund: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.Synonyms: F-box and WD-40 domain-containing protein 8, F-box only protein 29, F-box/WD repeat-containing protein 8, FBW6, FBW8, FBX29, FBXO29, FBXW6

Molekulargewicht: 67394 Da

Gen-ID: 26259

NCBI Accession: NP_036306