ERI2 Antikörper (Middle Region)
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- Target Alle ERI2 (EXOD1) Produkte
- ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))
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Bindungsspezifität
- AA 443-472, Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ERI2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human EXOD1 (Center).
- Aufreinigung
- Affinity Chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 443-472 amino acids from the Central region of Human EXOD1 Genename: ERI2
- Isotyp
- Ig Fraction
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))
- Andere Bezeichnung
- EXOD1 (EXOD1 Produkte)
- Synonyme
- exod1 antikoerper, EXOD1 antikoerper, Exod1 antikoerper, 4933424N09Rik antikoerper, mKIAA1504 antikoerper, eri2 antikoerper, ERI1 exoribonuclease family member 2 L homeolog antikoerper, ERI1 exoribonuclease family member 2 antikoerper, exoribonuclease 2 antikoerper, eri2.L antikoerper, ERI2 antikoerper, Eri2 antikoerper, eri2 antikoerper
- Hintergrund
- EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.Synonyms: Exonuclease domain-containing protein 1, KIAA1504, MGC16943
- Molekulargewicht
- 77401 Da
- Gen-ID
- 112479
- NCBI Accession
- NP_001136197
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