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ERI2 Antikörper (Middle Region)

EXOD1 Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN952142
  • Target Alle ERI2 (EXOD1) Produkte
    ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 443-472, Middle Region
    Reaktivität
    • 20
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 18
    • 2
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ERI2 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 13
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes Human EXOD1 (Center).
    Aufreinigung
    Affinity Chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 443-472 amino acids from the Central region of Human EXOD1 Genename: ERI2
    Isotyp
    Ig Fraction
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))
    Andere Bezeichnung
    EXOD1 (EXOD1 Produkte)
    Synonyme
    exod1 antikoerper, EXOD1 antikoerper, Exod1 antikoerper, 4933424N09Rik antikoerper, mKIAA1504 antikoerper, eri2 antikoerper, ERI1 exoribonuclease family member 2 L homeolog antikoerper, ERI1 exoribonuclease family member 2 antikoerper, exoribonuclease 2 antikoerper, eri2.L antikoerper, ERI2 antikoerper, Eri2 antikoerper, eri2 antikoerper
    Hintergrund
    EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.Synonyms: Exonuclease domain-containing protein 1, KIAA1504, MGC16943
    Molekulargewicht
    77401 Da
    Gen-ID
    112479
    NCBI Accession
    NP_001136197
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