MDS1 and EVI1 Complex Locus (MECOM) (AA 1-30), (N-Term) Antikörper

Details zu Produkt Nr. ABIN952135, Anbieter: Anmelden zum Anzeigen
Antigen
  • evi1
  • im:7140716
  • prdm3
  • EVI1
  • AML1-EVI-1
  • MDS1
  • MDS1-EVI1
  • PRDM3
  • D630039M04Rik
  • Evi-1
  • Evi1
  • Jbo
  • Mds
  • Mds1
  • Mds1-Evi1
  • Prdm3
  • Znfpr1b1
  • AML1
  • AMLCR1
  • CBFA2
  • EVI-1
  • PEBP2aB
  • MDS1 and EVI1 complex locus
  • runt-related transcription factor 1
  • mecom
  • MECOM
  • LOC100343228
  • Mecom
  • RUNX1
Epitop
N-Term, AA 1-30
28
17
16
15
9
5
5
4
4
3
3
2
2
2
1
1
1
1
1
Reaktivität
Human
105
34
9
4
4
3
3
2
1
1
1
Wirt
Kaninchen
71
31
15
Klonalität
Polyklonal
Konjugat
Unkonjugiert
6
6
6
6
6
6
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
104
65
11
5
3
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human EVI1. Genename: MECOM
Isotyp Ig
Spezifität This antibody recognizes Human EVI1 (N-term).
Reinigung Affinity Chromatography on Protein A
Andere Bezeichnung EVI1 (MECOM Antibody Abstract)
Hintergrund EVI1 functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.Synonyms: EVI-1, Ecotropic virus integration site 1 protein homolog, MDS1 and EVI1 complex locus protein EVI1, MECOM
Molekulargewicht 118276 Da
Gen-ID 2122
NCBI Accession NP_001098547
Forschungsgebiet Chromatin and Nuclear Signaling, Chromatin Binding Proteins, Cell Cycle
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Western Blotting (WB) image for anti-MDS1 and EVI1 Complex Locus (MECOM) (AA 1-30), (N-Term) antibody (ABIN952135) Western blot analysis of EVI1 Antibody (N-term) in CEM cell line lysates (35ug/lane)....
Allgemeine Veröffentlichungen Gómez-Benito, Conchillo, García, Vázquez, Maicas, Vicente, Cristobal, Marcotegui, García-Ortí, Bandrés, Calasanz, Alonso, Odero: "EVI1 controls proliferation in acute myeloid leukaemia through modulation of miR-1-2." in: British journal of cancer, Vol. 103, Issue 8, pp. 1292-6, 2010 (PubMed).

Goyama, Kurokawa: "Evi-1 as a critical regulator of leukemic cells." in: International journal of hematology, Vol. 91, Issue 5, pp. 753-7, 2010 (PubMed).

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