F7
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB54990
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1,0 mg/mL
Buffer
PBS containing 0.02 % sodium azide (NaN3) as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Schut, Kirschbaum, Adelmeijer, de Groot, Lisman: "In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug." in: British journal of haematology, (2016) (PubMed).
Human blood coagulation factor VII is a 50 kD, vitamin K dependent, plasma glycoprotein synthesized in the liver and secreted into the blood as a single chain zymogen of serine protease factor VIIa. Factor VII participates in a cascade of reactions leading to the coagulation of blood and contains two Epidermal Growth Factor (EGF) domains. This antibody recognizes an epitope in the first EGF-like domain of factor VII/VIIa. Factor VII participates in the extrinsic pathway of blood coagulation in an Activated form called factor VIIa. Factor VII can be converted to VIIa by Factor IXa or thrombin.Synonyms: Proconvertin, SPCA, Serum prothrombin conversion accelerator