CHRNA10 Antikörper (Middle Region)

Produktnummer ABIN951514

Produktdetails anti-CHRNA10 Antikörper

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Bindungsspezifität: AA 186-214, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to CHRNA10.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 186-214 amino acids from the Central region of human CHRNA10

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CHRNA10

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Andere Bezeichnung: CHRNA10 (CHRNA10 Produkte)

Synonyme: si:dkey-24p1.3 antikoerper, ALPHA 10 nAChR antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 10 antikoerper, cholinergic receptor nicotinic alpha 10 subunit antikoerper, cholinergic receptor, nicotinic, alpha 10a antikoerper, neuronal acetylcholine receptor subunit alpha-10 antikoerper, cholinergic receptor, nicotinic, alpha 10 (neuronal) antikoerper, Chrna10 antikoerper, CHRNA10 antikoerper, chrna10a antikoerper, LOC100344381 antikoerper

Hintergrund: CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.Synonyms: NACHR alpha-10, NACHRA10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10

Molekulargewicht: 49705 Da

Gen-ID: 57053

NCBI Accession: NP_065135

Pathways: Sensory Perception of Sound, Synaptic Membrane