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CD8B Antikörper (Biotin)

CD8B Reaktivität: Maus FACS Wirt: Ratte Monoclonal CT-CD8b Biotin
Produktnummer ABIN951402
  • Target Alle CD8B Antikörper anzeigen
    CD8B (CD8b Molecule (CD8B))
    Reaktivität
    • 74
    • 38
    • 23
    • 13
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 77
    • 39
    • 28
    Ratte
    Klonalität
    • 78
    • 65
    • 1
    Monoklonal
    Konjugat
    • 60
    • 17
    • 16
    • 13
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD8B Antikörper ist konjugiert mit Biotin
    Applikation
    • 79
    • 78
    • 45
    • 25
    • 16
    • 16
    • 13
    • 13
    • 10
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This anti-mouse CD8β Chain monoclonal antibody reacts with the mouse CD8 chain. The CD8 β Chain is also named Ly-3. The CD8 chain associates with the CD8 chain to form the CD8 / heterodimer on MHC class I restricted T-cells (cytotoxic T cells) and most thymocytes1. Since a small subset of T cells (IEL cells) express CD8 / homodimers rather than CD8 / heterodimers, investigators should use an antibody directed against the CD8 chain (CL168B, clone CT-CD8a) to definitively label mouse CD8 cells.
    Klon
    CT-CD8b
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD8B Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS, 0.1 % NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C. Should this product contain a precipitate we recommend microcentrifugation before use.
  • Target
    CD8B (CD8b Molecule (CD8B))
    Andere Bezeichnung
    CD8 beta (CD8B Produkte)
    Synonyme
    Cd8b antikoerper, Ly-3 antikoerper, Ly-C antikoerper, Lyt-3 antikoerper, CD8B1 antikoerper, LEU2 antikoerper, LY3 antikoerper, LYT3 antikoerper, P37 antikoerper, Cd8b1 antikoerper, CD8b molecule antikoerper, CD8 antigen, beta chain 1 antikoerper, Cd8b antikoerper, CD8B antikoerper, Cd8b1 antikoerper
    Hintergrund
    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain
    Gen-ID
    12526
    NCBI Accession
    NP_033988
    UniProt
    P10300
    Pathways
    T-Zell Rezeptor Signalweg
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