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- Target Alle PD-1 (PDCD1) Antikörper anzeigen
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Reaktivität
- Maus
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser PD-1 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- This Monoclonal Antibody reacts with Mouse PD-1 (Programmed Death-1).
- Aufreinigung
- Protein G Chromatography
- Immunogen
- PD-1 cDNA transfectant. Donor: mouse ascites fluid. Fusion Partner: Mouse myeloma P3U1.
- Klon
- J43
- Isotyp
- IgG
- Top Product
- Discover our top product PDCD1 Primärantikörper
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anti-Programmed Cell Death 1 (PDCD1) (AA 201-288) antibody
PDCD1 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 41-132) antibodyPDCD1 Reaktivität: Human WB, ELISA, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 192-288) antibodyPDCD1 Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 8G5B12 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 192-288) antibodyPDCD1 Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 3B3D9 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 Reaktivität: Human FACS, WB, IHC, ELISA, ICC, Neut Wirt: Maus Monoclonal 3E12A10 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 Reaktivität: Human FACS, WB, IHC, ELISA, ICC, Neut Wirt: Maus Monoclonal 1D6F6 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibodyPDCD1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) antibodyPDCD1 Reaktivität: Human IHC, ELISA, StM, Coat Wirt: Maus Monoclonal PDCD1-2720 unconjugated
anti-Programmed Cell Death 1 (PDCD1) (AA 1-288) antibodyPDCD1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Programmed Cell Death 1 (PDCD1) antibodyPDCD1 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal EH12-2H7 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Andere Bezeichnung
- CD279 / PD1 (PDCD1 Produkte)
- Synonyme
- CD279 antikoerper, PD-1 antikoerper, PD1 antikoerper, SLEB2 antikoerper, hPD-1 antikoerper, hPD-l antikoerper, Ly101 antikoerper, Pdc1 antikoerper, programmed cell death 1 antikoerper, PDCD1 antikoerper, Pdcd1 antikoerper
- Hintergrund
- CD279 is 50-55kD membrane protein which is a member of the CD28 family, and functions mainly as a negative regulator of T-cell activation. CD279 has two specific ligands, CD274 (PD-L1) and CD273 (PD-L2), and their interaction is key in the balance between stimulatory and inhibitory signals needed for effective immune responses to microbes and self-tolerance. CD279 is inducibly expressed by T-cells, B-cells, NK-T-cells and monocytes upon activation. Loss of CD279 function has been associated with a number of autoimmune diseases, including rheumatoid arthritis, type I diabetes and ankylosing spondylitis. Recent studies suggest that CD279 could be targeted therapeutically in the treatment of HIV infection to reduce T-cell exhaustion.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1
- Gen-ID
- 18566
- NCBI Accession
- NP_032824
- UniProt
- Q02242
- Pathways
- Cancer Immune Checkpoints
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