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CTLA4 Antikörper (FITC)

CTLA4 Reaktivität: Human FACS Wirt: Maus Monoclonal A3-4H2-H12 FITC
Produktnummer ABIN951193
  • Target Alle CTLA4 Antikörper anzeigen
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Reaktivität
    • 96
    • 67
    • 35
    • 5
    • 4
    Human
    Wirt
    • 62
    • 52
    • 18
    • 12
    • 1
    • 1
    Maus
    Klonalität
    • 89
    • 54
    • 2
    Monoklonal
    Konjugat
    • 68
    • 17
    • 13
    • 12
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CTLA4 Antikörper ist konjugiert mit FITC
    Applikation
    • 87
    • 66
    • 52
    • 35
    • 19
    • 17
    • 14
    • 13
    • 10
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Recognizes Human CTLA-4 (CD152).
    Aufreinigung
    Affinity Chromatography on Protein G
    Immunogen
    Activated T cells Donor: Balb/c mouse Fusion Partner: SP 2/0 myeloma
    Klon
    A3-4H2-H12
    Isotyp
    IgG2a
    Top Product
    Discover our top product CTLA4 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Andere Bezeichnung
    CD152 / CTLA4 (CTLA4 Produkte)
    Synonyme
    CTLA-4 antikoerper, CTLA4 antikoerper, CD152 antikoerper, Cd152 antikoerper, Ctla-4 antikoerper, Ly-56 antikoerper, CD antikoerper, CELIAC3 antikoerper, GRD4 antikoerper, GSE antikoerper, IDDM12 antikoerper, sCTLA4 antikoerper, cytotoxic T-lymphocyte associated protein 4 antikoerper, cytotoxic T-lymphocyte-associated protein 4 antikoerper, CTLA4 antikoerper, Ctla4 antikoerper
    Hintergrund
    Human CTLA-4 (also known as Cytotoxic T lymphocyte-associated antigen-4, CD152) is a structural homologue of T cell co-stimulatory receptor CD28. CTLA-4 binds to the same ligands (CD80 and CD86) as CD28 but with much higher avidity. It is expressed at very low levels on the cell surface of activated T cells, and is found primarily in the post-Golgi or endosomal compartments of the cell. There is a high degree of overall homology between human and mouse CTLA-4 (>70 % ), and the cytoplasmic domains of the human, mouse and rabbit sequences are completely conserved. CD152 antibodies have shown both stimulatory and negative regulatory roles in functional experiments.Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
    Gen-ID
    1493
    NCBI Accession
    NP_001032720
    UniProt
    P16410
    Pathways
    Cancer Immune Checkpoints
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