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CTLA4 Antikörper (FITC)
CTLA4
Reaktivität: Human
FACS
Wirt: Maus
Monoclonal
A3-4H2-H12
FITC
Produktdetails anti-CTLA4 Antikörper (FITC)
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Target
Alle CTLA4 Antikörper anzeigen
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Reaktivität
Alle Reaktivitäten für CTLA4 Antikörper
Human
Wirt
Alle Wirte für CTLA4 Antikörper
Maus
Klonalität
Alle Klonalitäten für CTLA4 Antikörper
Monoklonal
Konjugat
Alle Konjugate für CTLA4 Antikörper
Dieser CTLA4 Antikörper ist konjugiert mit FITC
Applikation
Alle Applikationen für CTLA4 Antikörper
Flow Cytometry (FACS)
Spezifität
Recognizes Human CTLA-4 (CD152).
Aufreinigung
Affinity Chromatography on Protein G
Immunogen
Activated T cells Donor: Balb/c mouse Fusion Partner: SP 2/0 myeloma
Klon
A3-4H2-H12
Isotyp
IgG2a
Top Product
Discover our top product CTLA4 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.1 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu CTLA4
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Target
CTLA4
(Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Andere Bezeichnung
CD152 / CTLA4 (CTLA4 Produkte )
Synonyme
CTLA-4 antikoerper, CTLA4 antikoerper, CD152 antikoerper, Cd152 antikoerper, Ctla-4 antikoerper, Ly-56 antikoerper, CD antikoerper, CELIAC3 antikoerper, GRD4 antikoerper, GSE antikoerper, IDDM12 antikoerper, sCTLA4 antikoerper, cytotoxic T-lymphocyte associated protein 4 antikoerper, cytotoxic T-lymphocyte-associated protein 4 antikoerper, CTLA4 antikoerper, Ctla4 antikoerper
Hintergrund
Human CTLA-4 (also known as Cytotoxic T lymphocyte-associated antigen-4, CD152) is a structural homologue of T cell co-stimulatory receptor CD28. CTLA-4 binds to the same ligands (CD80 and CD86) as CD28 but with much higher avidity. It is expressed at very low levels on the cell surface of activated T cells, and is found primarily in the post-Golgi or endosomal compartments of the cell. There is a high degree of overall homology between human and mouse CTLA-4 (>70 % ), and the cytoplasmic domains of the human, mouse and rabbit sequences are completely conserved. CD152 antibodies have shown both stimulatory and negative regulatory roles in functional experiments.Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Gen-ID
1493
NCBI Accession
NP_001032720
UniProt
P16410
Pathways
Cancer Immune Checkpoints
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