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CD130/gp130 Antikörper (C-Term)
IL6ST
Reaktivität: Human
WB, IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-CD130/gp130 Antikörper
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Target
Alle CD130/gp130 (IL6ST) Antikörper anzeigen
CD130/gp130 (IL6ST)
(Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
Bindungsspezifität
Alle Epitope für CD130/gp130 Antikörper
AA 878-906, C-Term
Reaktivität
Alle Reaktivitäten für CD130/gp130 Antikörper
Human
Wirt
Alle Wirte für CD130/gp130 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für CD130/gp130 Antikörper
Polyklonal
Konjugat
Alle Konjugate für CD130/gp130 Antikörper
Dieser CD130/gp130 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CD130/gp130 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
This antibody reacts to CD130.
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 878-906 amino acids from the C-terminal region of human CD130
Isotyp
Ig Fraction
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu CD130/gp130
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Target
CD130/gp130 (IL6ST)
(Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
Andere Bezeichnung
CD130 / IL6ST (IL6ST Produkte )
Synonyme
CD130 antikoerper, CDW130 antikoerper, GP130 antikoerper, IL-6RB antikoerper, 5133400A03Rik antikoerper, AA389424 antikoerper, BB405851 antikoerper, D13Ertd699e antikoerper, gp130 antikoerper, Ac1055 antikoerper, Gp130 antikoerper, Il-6rb antikoerper, IL-6 antikoerper, interleukin 6 signal transducer antikoerper, IL6ST antikoerper, Il6st antikoerper, il6st antikoerper
Hintergrund
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17.Synonyms: IL-6R-beta, IL6 receptor beta, Interleukin-6 receptor subunit beta
Molekulargewicht
103537 Da
Gen-ID
3572
NCBI Accession
NP_002175
Pathways
JAK-STAT Signalweg , Cellular Glucan Metabolic Process , Autophagie , Smooth Muscle Cell Migration , Cancer Immune Checkpoints
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