C4BPB Antikörper (Middle Region)

Produktnummer ABIN950920

Produktdetails anti-C4BPB Antikörper

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Bindungsspezifität: AA 124-153, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C4BPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to C4b-binding protein beta.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 124-153 amino acids from the Central region of human C4BPB

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu C4BPB

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Andere Bezeichnung: C4b-Binding Protein beta (C4BPB Produkte)

Synonyme: C4BPB antikoerper, C4BP antikoerper, C4bp-ps1 antikoerper, complement component 4 binding protein beta antikoerper, complement component 4 binding protein, beta antikoerper, C4BPB antikoerper, C4bpb antikoerper

Hintergrund: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.Synonyms: C4BPB

Gen-ID: 725

NCBI Accession: NP_001017365

Pathways: Komplementsystem