BCLAF1 Antikörper (BCL2-Associated Transcription Factor 1) (AA 658-688)

Details for Product anti-BCLAF1 Antibody No. ABIN950638, Anbieter: Anmelden zum Anzeigen
Antigen
  • BCLAF1
  • btf
  • bk211l9.1
  • DKFZp468F0113
  • BTF
  • bK211L9.1
  • 2610102K23Rik
  • 2700025J07Rik
  • 2810454G14Rik
  • 5730534O06Rik
  • AI450190
  • AW556225
  • Btf
  • mKIAA0164
  • Aa2-041
  • Fam54a
  • Mtfr2
  • BCL2-associated transcription factor 1
  • BCLAF1
  • bclaf1
  • LOC100231845
  • LOC100339738
  • LOC100351429
  • Bclaf1
Epitop
AA 658-688, C-Term
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9
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2
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1
Reaktivität
Human
96
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25
10
4
4
4
3
3
2
2
2
2
2
1
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1
Wirt
Kaninchen
77
20
Klonalität
Polyklonal
Konjugat
Dieser BCLAF1 Antikörper ist unkonjugiert
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2
1
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Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
77
40
38
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12
5
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide between 658-688 amino acids from the C-terminal region of human BCLAF1
Isotyp Ig
Spezifität This antibody reacts to BCLAF1.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Affinity chromatography on Protein A
Andere Bezeichnung BCLAF1 / BTF (BCLAF1 Antibody Abstract)
Hintergrund This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Aa2-041, Bcl-2-associated transcription factor 1, KIAA0164
Gen-ID 9774
NCBI Accession NP_001070908
Pathways Positive Regulation of Response to DNA Damage Stimulus
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2-Associated Transcription Factor 1 (BCLAF1) (AA 658-688), (C-Term) antibody (ABIN950638) BCLAF1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin...
Western Blotting (WB) image for anti-BCL2-Associated Transcription Factor 1 (BCLAF1) (AA 658-688), (C-Term) antibody (ABIN950638) BCLAF1 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35µg/lane)...
Allgemeine Veröffentlichungen Sarras, Alizadeh Azami, McPherson: "In search of a function for BCLAF1." in: TheScientificWorldJournal, Vol. 10, pp. 1450-61, 2010 (PubMed).

Rénert, Leprince, Dieu, Renaut, Raes, Bours, Chapelle, Piette, Merville, Fillet: "The proapoptotic C16-ceramide-dependent pathway requires the death-promoting factor Btf in colon adenocarcinoma cells." in: Journal of proteome research, Vol. 8, Issue 10, pp. 4810-22, 2009 (PubMed).

Liu, Lu, Miki, Yoshida: "Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage." in: Molecular and cellular biology, Vol. 27, Issue 24, pp. 8480-91, 2007 (PubMed).

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